Parkinson disease

Question 1

Parkinson disease

Answer 1

Degeneration of dopaminergic neuron in substantia nigra in midbrain

Question 2

Diagnosis of Parkinson disease

Answer 2

Clinical diagnosis, at least 2 of the following to diagnose:
- bradykinesia,
cogwheel rigidity,
resting tremor (asymmetric at onset),
postural reflex abnormality (falling) result in chronic subdural hematoma

Question 3

medication induced parkinsonism (symmetrical at onset)

Answer 3

Metoclopramide, used in vomiting
Haloperidol and
Methyldopa antihypertensive used usually in pregnancy

Question 4

Early dementia within the first year of the appearance of parkinsonism is a hall mark
of

Answer 4

dementia with lewy body!
after 1 year = dementia due to parkinsonism

Question 5

Treatment of Parkinson disease

Answer 5

Levodopa with Carbidopa

Question 6

Degeneration of which site in brain is the cause of Parkinson disease?

Answer 6

Substantia nigra in midbrain

Question 7

70-year-old male came with Mask face,
bradykinesia, resting tremors, on examination:
shufing gate, what is the diagnosis?

Answer 7

Parkinson disease

Question 8

Parkinson disease, how to reach the diagnosis?

Answer 8

Clinical diagnosis

Question 9

Patient with history of gastroenteritis took
medication, now came with abnormal
movements in head and eyes, what is the
causative drug?

Answer 9

Metoclopramide