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Mango Notes > Part 1 (1-150) > Flashcards

Part 1 (1-150) Flashcards

1
Q

Agency in the US responsible for selecting
appropriate nonproprietary names for drugs

A

USAN

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2
Q

Official standards for individual drugs and
chemicals formulated into dosage forms are
published in the

A

USP/NF

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3
Q

Descriptions of the Federal Controlled
Substances Act, Approved Drug Products
with Therapeutic Equivalence Evaluations,
and USP/NF dispensing requirements may
be found in the

A

USP DI Volume III

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4
Q

Prescription drug descriptions expressed in a
layperson’s terms and useful as handouts for
patients may be photocopied from

A

US DI Volume II

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5
Q

Most frequently dispensed dosage form in
the US

A

Oral tablets

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6
Q

Classified as alternative medicine in the US EXCEPT

A

Allopathy

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7
Q

Alternative medical practice that stresses the
use of extremely small dose of drugs

A

Homeopathic medicine

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8
Q

Rate of disintegration for most commercial
tablets

A

sublingual -> uncoated -> coated

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9
Q

Tablet coatings used to mask the bitter tastes
of drugs

A

film, sugar

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10
Q

Diluent in tablet formulation EXCEPT

A

Magnesium stearate

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11
Q

Functions of lubricant in tablet formulation EXCEPT

A

improve tablet wetting in the stomach

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12
Q

Trademarked dosage form, enteric coated

A

Enseal

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13
Q

Sweetener that is widely employed in
chewable tablet formulation

A

Mannitol

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14
Q

Starch may be included in tablet formulation

A

Binder, disintegrant

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15
Q

Commission E Monographs are related to

A

Herbs

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16
Q

Specific drug is available both oral tablet and
liquid dosage forms

A

Liquid form absorbs faster

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17
Q

General characteristics true for alkaloids EXCEPT

A

pKa less than 7

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18
Q

Alkaloid powders exhibiting good water
solubility

A

Morphine HCl

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19
Q

Form of basic drug haloperidol with good
water solubility

A

HCl, lactate

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20
Q

Suitable as drug excipient EXCEPT

A

Benzocaine

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21
Q

Included in the drug solution as chelating
agent

A

Edetate

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22
Q

Ions effectively chelated

A

Lead

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23
Q

Solubility of a substance may be expressed
in several ways. When a quantitative
statement of solubility is given in USP, it is
generally expressed as

A

mL of solvent to dissolve 1g of solute

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24
Q

Although most drugs in pharmaceutical
dosage forms decompose following
first-order kinetics, exceptions are drugs
formulated in

A

Oral suspensions

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25
Q

Early sign of decomposing epinephrine
solution is the presence of

A

pink color

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26
Q

Process of grinding a substance to a very
fine powder

A

trituration

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27
Q

Term “impalpable” refers to a substance that
is

A

not perceptible to touch

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28
Q

Tartrazine may be included in drug products

A

coloring agent

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29
Q

Term “chiral” is related to a drug’s

A

stereoisomerism

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30
Q

Advantages of developing chiral forms of
drug

A

more direct action, economical

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31
Q

Different crystalline forms (polymorphs) of
the same drug exhibit different

A

melting point, solubility

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32
Q

Example of nonionic surfactant

A

sorbitan monopalmitate

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33
Q

Literature lists albuterol with two pKas of 9.3
and 10.3. Description most appropriate for
this drug

A

weak base

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34
Q

Patients following low sodium diets may
resort to the use of sodium-free salt
substitutes such as NoSalt. Major ingredient
in these products is

A

Potassium chloride

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35
Q

Potassium supplements are administered in EXCEPT

A

IV bolus

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36
Q

Statements true about fluorouracil EXCEPT

A

effective only when administered IV

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37
Q

Black box warning to a pharmacist

A

PI

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38
Q

Cautions found in drug product inserts in
order of least serious to most serious

A

Precaution, warning, CI

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39
Q

Comparison of individual amino acids
present in commercial amino acid injection
solution may be found in

A

Facts and comparison; Trissel’s handbook of injectable drugs

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40
Q

Release of an ingredient from packaging components into the actual product is best described by the term

A

leaching

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41
Q

Gauge numbers used to size hypodermic
needles reflect the needle

A

external diameter, cannula

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42
Q

Designation “winged” needles is most closely
associated with which type of injection

A

IV

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43
Q

Insulin preparations are usually administered
by

A

SC

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44
Q

Needle most suited for the administration of
insulin solutions

A

25G 5/8”

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45
Q

Term “venoclysis” is closely associated with

A

IV Infusion

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46
Q

Designation “mini bottles” refers to

A

partially filled parenteral with 50 to 150mL volume

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47
Q

Term “piggyback” is most commonly
associated with

A

Intermittent therapy

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48
Q

Refer to parenteral nutrition

A

TPN/TNA

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49
Q

Approximate maximum volume of fluid that
should be administered daily by IV infusion to
stabilized patient

A

4L

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50
Q

Although isotonicity is desirable for almost all
parenterals, it is particularly critical to

A

SC

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51
Q

Suspension is suitable for EXCEPT

A

IV

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52
Q

Most appropriate medical order requiring an
intravenous bolus injection

A

IVP

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53
Q

Even distribution of drug into the blood after
an IV bolus injection can be expected

A

within 4 mins

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54
Q

Quantities of all ingredients present in
parenteral solutions must be specified on the
label EXCEPT for

A

isotonicity, and pH adjustors

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55
Q

Usual expiration dating should be placed on
a parenteral admixture prepared in hospital
pharmacy

A

24hr

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56
Q

Parenteral solutions that are isotonic with
human RBCs have an osmolality of
approximately how many mOsm/L

A

300

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57
Q

Injectables isotonic with human RBCs

A

D5W; D 2.5/0.45NS

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58
Q

Osmotic pressure of 1 0.1-mol dextrose
solution will be approximately __ times that
of 0.1-mol sodium chloride solution

A

0.5

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59
Q

Parenteral solution considered most closely
approximate the extracellular fluid of the
human body

A

LRS (Hartmann)

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60
Q

Injection routes limited to volumes of ≤ 1 mL

A

SC

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61
Q

Parenteral antibiotic least suitable for
surgical prophylaxis

A

Tetracycline

62
Q

IM injection site suitable for a small child (<3
years of age)

A

Vastus lateralis

63
Q

Parenteral routes of administration
considered suitable for heparin sodium
injection USP

A

Continuous IV infusion, sc

64
Q

commonly employed for the administration of
insulin USP

A

Continuous IV infusion, im

65
Q

Regular insulin

A

can be otc, short plasma half-life

66
Q

Parenteral system “ADD-Vantage” is

A

vial attached to minibag of diluent

67
Q

IVAC’s controlled-release infusion system (CRIS) is best described as

A

plastic disposable adaptor

68
Q

Example of implantable catheter for the
administration of parenteral solution is

A

Port-A-Cath

69
Q

Pharmacy Bulk Packages

A

for prep of sterile parenterals, no antimicrobial preservative

70
Q

Parenteral container of potassium chloride concentrate must be packaged

A

black flip-off button

71
Q

Usual maximum volume allowed as a
parenteral package for Bacteriostatic Water for Injection

A

30 mL

72
Q

Benzyl alcohol is of specific danger in

A

Neonates

73
Q

Vitamins possess antioxidant properties

A

Ascorbic acid

74
Q

Parenteral antibiotic is most suitable in an aqueous solution

A

Gentamicin sulfate

75
Q

Biologicals can be used to obtain either
active or passive immunity

A

Active: Toxoid, vaccine
Passive: anti-serm, antitoxin, immune serum

76
Q

Vaccine used for active immunization against measles (rubeola)

A

Attenuvax

77
Q

Route of administration of tuberculin USP

A

ID

78
Q

Tuberculin syringes are

A

1mL w/ 0.05 accuracy

79
Q

Vaccines for administration to children EXCEPT

A

Herpes

80
Q

Immune serum globulin (gamma globulin) is usually administered by

A

IM

81
Q

Pediatrix is a combination vaccine for EXCEPT

A

Hepa C

82
Q

Vaccines NOT administered to pregnant
women

A

MMR

83
Q

Preparation induces passive rather than
active immunity

A

Botox

84
Q

Descriptions of toxoids EXCEPT

A

permanent immunity

85
Q

DTP series of injections is intended for
administration to

A

Infants

86
Q

Both Adacel and Boostix are examples of newer Tdap vaccines. Adcel differ from Boostix:

A

can be used for elders

87
Q

Good candidates for pneumonia vaccine

A

Geriatrics, young adults

88
Q

Usual storage condition specified for
biologicals

A

2-8

89
Q

Viral infections EXCEPT

A

Typhoid fever

90
Q

Techniques in the development of
“biotechnological drugs”

A

Gene splicing, monoclonal antibodies

91
Q

Used to prepare “targeted drug delivery
systems”

A

Liposomes, nanoparticles

92
Q

Most of the recently developed biotechnological drugs as formulated in this dosage form

A

parenteral

93
Q

Diagnostic test incorporates monoclonal antibodies into the testing procedure

A

ovulation, pregnancy

94
Q

Tablet which quickly dissolve in the mouth with the intent of being swallowed for GIT absorption

A

rapidly dissolving

95
Q

Mechanism OraSolv compressed tablet
disintegrates

A

effervescence

96
Q

Baxter intermates

A

elastomeric balloon

97
Q

PCA devices

A

Px may be ambulatory, bolus dosing

98
Q

Hospital pharmacist has reviewed several clinical papers concerning irritable bowel syndrome and is preparing a summary comparing the findings for publication.

A

Meta-analysis

99
Q

Client in retail pharmacy asks the pharmacist where she might find a new lotion product that contains ECAMSULE. Section of the pharmacy should the pharmacist direct her

A

sun screen

100
Q

Considered effective in the treatment of
accidental drug poisoning

A

activated charcoal, ipecac syrup

101
Q

Most iron salts are administered orally, a commercially available parenteral product

A

DexFerrum

102
Q

Iron sucrose injection

A

for iron deficiency anemia for pax undergoing hemodialysis

103
Q

Chemical is effective and safe drug in
treatment of either diarrhea or constipation

A

polycarbophil

104
Q

Simethicone is most likely to be included in this type of OTC product

A

antacid

105
Q

Ingredient substituted in many OTC
antidiarrheal product as a replacement for the adsorbent attapulgite

A

bismuth subsalicylate

106
Q

Suggested dosing regimen for loperamide 2 mg tablets for diarrhea

A

immediate 2 tab, one tab after loose stool

107
Q

Common building block for liposomes

A

phospholipid

108
Q

Liposomal dosage forms can be
administered

A

parenteral, oral, topical

109
Q

Parenteral products have been formulated into liposomal dosage forms

A

amphotericin, daunorubicin

110
Q

Doxorubicin HCl (Doxil) liposomal formula

A

stealth liposomes

111
Q

OTC internal analgesics contains
magnesium salicylate

A

Doan’s original

112
Q

Dextromethorphan as cough suppressant EXCEPT

A

max adult dose 30mg

113
Q

Disadvantages of calcium carbonate EXCEPT

A

Capacity for acid neutralization is poor

114
Q

Contain calcium carbonate as active ingredient

A

Rolaids/Titralac chewable tab

115
Q

Antacid product is a chemical combination of aluminum and magnesium hydroxides

A

Riopan

116
Q

Drugs have label warnings against their use during pregnancy especially during the last trimester

A

Aspirin, Ibuprofen

117
Q

Statement about bisacodyl EXCEPT

A

Tablets may be administered with milk to avoid GI irritation

118
Q

OTC products containing bisacodyl as active ingredient EXCEPT

A

ExLax, Regular

119
Q

Tablet dissolution EXCEPT

A

Increasing tab compression, increases dissolution

120
Q

Product label indicates storage in a
refrigerator

A

Cold: 2-8

121
Q

Patient requests a container of Abreva.
Section of pharmacy would this product be likely stocked

A

Cold sore

122
Q

Aspertame is included in some drug products

A

sweetener

123
Q

Term “circadian rhythm” refers

A

cycle approx. 24 hr

124
Q

Antihypertensive drug product that is based on circadian rhythm

A

Covera-HS (Verapamil)

125
Q

Properties desirable in a pharmaceutical suspension

A

Pseudoplastic flow, thixotrophy

126
Q

Inhalation aerosol dosage forms

A

avoid first-pass effect, rapid onset

127
Q

Internal analgesic products contain
ketoprofen

A

actron

128
Q

Characteristic of first-degree burn

A

erythema, pain, no blister

129
Q

Dextranomer (Debrisan by Johnson & Johnson) EXCEPT

A

Effective in healing both secreting nad nonsecreting wound

130
Q

Effective local anesthetics present in OTC burn remedies

A

benzocaine; lidocaine

131
Q

For effectiveness as local anesthetic, the
level of benzocaine in a topical preparation should

A

at least 5%

132
Q

“French” scale commonly used for denoting diameters of

A

Urinary catheter & enteral feeding tube

133
Q

Basal thermometer

A

estimate ovulation

134
Q

Rectal clinical thermometers differ from oral thermometers in

A

bulb shape

135
Q

Allergic reactions to insect bites and stings EXCEPT

A

Toxicity of venom main cause of death

136
Q

Emergency insect sting and bite kits contains EXCEPT

A

Torniquet

137
Q

Ointment contains 2,000 units of enzyme per gram. Drug’s half-life if the decomposition rate is calculated to be 50 units per month

A

20 months

138
Q

Manufacturer’s decides to market the above enzyme
ointment at higher strength of 4,000 units per gram.
Approximate expiration date if standard of not less than
90% labeled claim is established

A

8 months

139
Q

Pamabrom is present in certain OTC
products as

A

Diuretic

140
Q

Ingredient has been recognized by FDA for the removal of ear cerumen

A

Carbamide peroxide

141
Q

Improve the absorption of drug into the skin EXCEPT

A

ointment base with excellent solubility

142
Q

Melatonin is available in some products

A

sleep aid

143
Q

Most appropriate procedure for using
Melatonin to prevent jet lag

A

take after reaching diff time zone

144
Q

Most commercial vaginal suppositories

A

PEG

145
Q

Diluent usually used for compressed vaginal tablet formulation

A

Lactose

146
Q

Rectal drug administration except

A

predictable release and absorption

147
Q

Vaginal suppository with contraceptive property

A

Semicid

148
Q

Carbomers included in topical products

A

thickening agent

149
Q

Colligative properties are useful in
determining

A

tonicity

150
Q

Colligative properties of solution

A

Related to total number of solute

Mango Notes (2 decks)

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