PASSMED

Question 1

Time frame for dresslers syndrome

Answer 1

2-6 weeks post-MI

Question 2

Treatment of Dresslers syndrome

Answer 2

aspirin and corticosteroids

Question 3

most likely diagnosis with fever and new murmur

Answer 3

bacterial endocarditis

Question 4

time frame of myocardial ischaemia post-MI

Answer 4

3 days (then macrophages infiltrate, granulation tissue)

Question 5

What is blue discolouration of flank areas a sign of?

Answer 5

Grey Turner’s sign -evidence of blood pooling in the retroperitoneal space. This happens as the pancreas is a retroperitoneal organ and inflammation can result in blood collecting in this space

Question 6

which antibiotics can cause torades de pointes

Answer 6

Macrolides can cause Torsades de pointes (‘twisting of the points’) - form of polymorphic ventricular tachycardia associated with a long QT interval. It may deteriorate into ventricular fibrillation and hence lead to sudden death.

Question 7

Bioavailibility of IV drugs

Answer 7

100%

Question 8

investigation of choice to confirm bronchiectasis

Answer 8

high resolution CT scan

Question 9

what cytokine activates macrophages

Answer 9

interferon gamma

Question 10

how does hypokalaemia present on ECG

Answer 10

U Wave
small or absent T waves (occasionally inversion)
prolong PR interval
ST depression
long QT