Pathology Flashcards
1
Q
Features of nephrotic syndrome
A
- edema
- proteinuria
- hypoalbuminemia
- hyperlipidemia
- noninflammatory, no dysmorphic RBCs, no RBC casts
2
Q
Key cell of nephrotic syndrome
A
visceral epithelial cell (podocyte)
3
Q
Features of nephritic syndrome
A
- urinary sediments
- inflammation
- HTN
- high Creatinine (renal insufficiency)
- severe crescents
- hematuria
4
Q
Key cell of nephritic syndrome
A
endothelial cell
5
Q
Hyaline casts
A
most common cast, precipitation of Tamm Horsfall mucoprotein (secreted by renal tubular cells)
6
Q
Granular casts
A
2nd most common, aggregates of plasma proteins (albumin, or IgLC), signify severe renal disease
7
Q
Fatty casts
A
from breakdown of lipid rich epithelial cells, if they include cholesterol they are Maltese crosses (indicate lipiduria)
8
Q
RBC casts
A
indicate glomerular damage
9
Q
WBC casts
A
indicate inflammation due to pyelonephritic, interstitial nephritis, post streptococcal nephritis
