Pathology of GI Tract

Question 1

Name the three types of cell present in the small bowel?

Answer 1

• Goblet cell
• Columnar absorptive cells
• Endocrine cells

Question 2

Where is the Meissener plexus?

Answer 2

• The submucosa

Question 3

Where is the Aeurbachs plexus?

Answer 3

• Between the longitudinal and circular muscle layer

Question 4

What gene mutation is associated with CD?

Answer 4

• NOD2

Question 5

What gene mutations is associated with UC

Answer 5

• HLA

Question 6

What is ischemic enteritis?

Answer 6

Inflammation of the SI/LI due to inadequate oxygen supply

- Occlusion of any of the 3 major GI artiers, the celiac trunk, super/inferior mesenteric could cause this

Question 7

What is radiation colitis?

Answer 7

• Abdominal irritation of the abdominal mucosa causing bleeding
• Radiotherapy causes this and usually occurs in pevlic/sigmoid colon/rectum cancer patients

Question 8

How does right sided adenocarcinoma differ from left sided colorectal adenocarcinoma

Answer 8

Right sided
- Altered blood PR
- Vague pain
- Weakness 
- Obstruction
Left sided
- Napkin skin lesion
- Fresh/altered blood
- Altered bowel habit