Pathophysiology Flashcards
What is the scientific term for “Tumour”
Neoplasm
What is the process of APOPTOSIS
break down and removal of unneeded or damaged cells
What DNA type is often associated with cancer? and whats its purpose
proto-oncogene, growth and proliferation
If the proto-oncogene cell is damaged by sunlight etc.. what does it turn into?
Activated oncogene
What is the danger with Activated oncogene?
They rapidly divide but send out no signals. Uncontrolled cell growth
what happens when the gene becomes a deactivated tumour suppressor gene?
Prevents cell responding to what its meant to- resistant to cell death
Once a a deactivated tumour suppressor gene what happens to the shape of the protein?
Changes, DNA code isn’t recognised for what it should be.
is just one mutated gene enough to cause cancer?
No (typically 5/6)
how many mutations ate required with bowel cancer?
Typically 11
what are the role of telomeres?
Like the plastic cap of shoe laces, protects genetic information when cells divide
what happens to telomeres with an immortal cell?
Telomerase keeps adding onto the telomere so cell never stops duplicating or will never die
what is the role of telomerase?
Continually builds up the telomeres.
