Penicillins

Question 1

What are the three penicillin categories?

Answer 1

1. Beta-lactamase sensitive
2. Broad spectrum
3. Penicillin resistant

Question 2

What is beta-lactamase?

Answer 2

its an enzyme which is produced by bacteria and provides multi-resistant to beta-lactamase antibiotics

Question 3

Which penicillins are more sensitive to beta-lactamase?

Answer 3

Phenoxymethylpenicillin

Benzylpenicillin

Question 4

Name broad spectrum antibiotics.

Answer 4

Amoxicillin and ampicillin

Question 5

Name a penicillin resistant antibiotic.

Answer 5

Flucloxacillin

Question 6

Which type of infections are penicillins generally good at fighting against?

Answer 6

Gram-positive and gram negative
are used for all infections
(RTI, pneumonia)

Question 7

What are the common S/E of penicillins?

Answer 7

Hypersensitivity
anaphylaxis
diarrhoea

Question 8

Whats the main S/E of flucloxacillin?

Answer 8

Hepatic disease especially in those taking it long-term.

Question 9

What S/E would you look for if a patient is taking flucloxacillin long term?

Answer 9

Cholestatic Jaundice, hepatitis

Question 10

What are the main S/E of ampicillin and amoxicilin?

Answer 10

rashes

Question 11

Which penicillins should be taken on an empty stomach?

Answer 11

Flucloxacillin, ampicillin, phenoxymethylpenicillin
This means 1 hour before food or 2 hours after food.
These three are the only ones taken before food.