PH1123 - Random Flashcards

1
Q

What is germination

A

Germination is the process by which a spore can revert into a vegetative bacterium

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2
Q

Use of broad spectrum antibiotics for extended time periods can give rise to severe gastroenteritis due to toxins produced by which bacterium?

A

Clostridium difficile

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3
Q

Which of the following normal flora represent a pathogenic organism that may commonly colonise the skin of patients and staff but does no cause a disease?

A

S. aureus

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4
Q

Is an abundance of exotoxins required to cause disease ?

A

No they are only required in small amounts

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5
Q

How would you best describe endotoxins and exotoxins ?

A

Exotoxins and endotoxins can be associated with severe pathogenicity

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6
Q

In severe food poisoning caused by consumption of food containing the exotoxin produced by Clostridium botulinum, what happens to the individual after consumption?

A

Paralysis, respiratory failure and death

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7
Q

Which drug used to treat Mycobacterium tuberculosis (TB) stops lipid production in the cell envelope?

A

Isoniazid

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8
Q

Why is it difficult to treat Mycobacterium tuberculosis infection?

A

M. tuberculosis has an outer membrane composed of lipopolysaccharides

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9
Q

What are exotoxins made out of and what are endotoxins made out of ?

A
exotoxins = It is polypeptide
endotoxins = It is lipopolysaccharide complex.
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10
Q

Which one of the following bacterial structure prevents phagocytosis?

A

the capsule

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11
Q

Which of the following source of contamination is forbidden in clean rooms where pharmaceutical products are being manufactured ?

A

drains

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12
Q

what is a probiotic ?

A

A probiotic is an oil oxidising microorganism that decomposes oil.

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13
Q

Which enzyme is produced by a bacterium and used to reduced blood clots?

A

Streptokinase

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14
Q

Which chemical is used for gas sterilisation?

A

Ethylene oxide

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15
Q

Which method can be used to reduce microbial contamination from a sample of water, the atmosphere and equipment?

A

Chemical treatment

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16
Q

which of the following interventions is not appropriate to reduce microbial count in water?

A

Boiling

17
Q

What is the name of the type of bacteria loosely associated with the skin surface?

A

Transient

18
Q

What chemical treatment can be used to reduce microbial count from water samples?

A

Chlorine and sodium hypochlorite