Pharm Flashcards
Which drug may increase risk of recurrence of breast cancer?
Fluoxetine (SSRI)
SSRI interaction can increase blood concentrations of which drugs?
warfarin
Tricyclic antidepressants
theophylline
tamoxifen (stops breakdown to active form)
Which anti-depressant has least sexual side effects?
Bupropion
What happens with a TCA overdose?
3Cs:
Coma
Convulsions
Cardiovascular (arrythmias)
Drug classes for general maintenance of bipolar disorders?
Lithium, valproate, carbamazapine, lamotrigine, olanzapine
Drug classes for manic phase of bipolar disorders?
Antipsychotics plus mood stabilizers
Drug classes for depressive phase of bipolar disorders?
Mild: mood stablizer alone (e.g. lamotrigine or lithium)
Severe: antidepressant (SSRIs) plus mood stabilizer/ atypical antipsychotic (e.g. buprioprion)