Pharm Flashcards

1
Q

Which drug may increase risk of recurrence of breast cancer?

A

Fluoxetine (SSRI)

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2
Q

SSRI interaction can increase blood concentrations of which drugs?

A

warfarin
Tricyclic antidepressants
theophylline
tamoxifen (stops breakdown to active form)

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3
Q

Which anti-depressant has least sexual side effects?

A

Bupropion

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4
Q

What happens with a TCA overdose?

A

3Cs:
Coma
Convulsions
Cardiovascular (arrythmias)

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5
Q

Drug classes for general maintenance of bipolar disorders?

A

Lithium, valproate, carbamazapine, lamotrigine, olanzapine

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6
Q

Drug classes for manic phase of bipolar disorders?

A

Antipsychotics plus mood stabilizers

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7
Q

Drug classes for depressive phase of bipolar disorders?

A

Mild: mood stablizer alone (e.g. lamotrigine or lithium)

Severe: antidepressant (SSRIs) plus mood stabilizer/ atypical antipsychotic (e.g. buprioprion)

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