Pharm 5 - Obesity Tx Flashcards

1
Q

things that cause obesity

A

steroids, atypical antipsy, insulin

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2
Q

things that reduce obesity

A

orlistate, phentermine, sibutramine, exenatide, topiramate

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3
Q

function of phentermine

A

increase satiety

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4
Q

type of drug that phentermine is

A

attenuated amphetamine

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5
Q

serotonergic 5-HT2C agonist

A

lorcaserin

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6
Q

function of lorcaserin

A

HT satiety

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7
Q

GLP-1 drug

A

exenatide

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8
Q

opioid antagonist that blocks food intake

A

naltrexone

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9
Q

naltrexone + bupropion =

A

contrave

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10
Q

function of naltrexone

A

block POMC reuptake

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11
Q

function of bupropion

A

inhibit adrenergic uptake = block food drive

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12
Q

seizure drug that loses weight

A

topiramate

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13
Q

potential mechanism for weight loss in topiramte

A

GluR5 blocker

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14
Q

fat absorption blocker drug

A

orlistat

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15
Q

% of fat not absorped in orlistate

A

30%

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16
Q

side effects of orlistat

A

diarrhea, bloating, fat soluble vit deficiency

17
Q

qualifiers for bariatric surgery

A

> 40 or >35 + comorbidity

18
Q

roux-en-y is what kind of surgery

A

bypass + pouch

19
Q

gastric banding is what kind of surgery

A

pouch only

20
Q

% of pt that fail bariatric surgery

A

20-30%