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Neuro Midterm > Pharm Rx > Flashcards

Pharm Rx Flashcards

1
Q

Fluoxetine

A 
SSRI: 5-HT-specific reuptake inhibition of serotonin
Antidepressant
Takes 4-8 weeks to have effects
Side effects: sexual dysfunction, GI
Risk: serotonin syndrome
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2
Q

Paroxetine

A 
SSRI: 5-HT-specific reuptake inhibition of serotonin
Antidepressant
Takes 4-8 weeks to have effects
Side effects: sexual dysfunction, GI
Risk: serotonin syndrome
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3
Q

Sertraline

A 
SSRI: 5-HT-specific reuptake inhibition of serotonin
Antidepressant
Takes 4-8 weeks to have effects
Side effects: sexual dysfunction, GI
Risk: serotonin syndrome
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4
Q

Citalopram

A 
SSRI: 5-HT-specific reuptake inhibition of serotonin
Antidepressant
Takes 4-8 weeks to have effects
Side effects: sexual dysfunction, GI
Risk: serotonin syndrome
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5
Q

Venlafaxine

A

SNRI: inhibit 5-HT (serotonin) and NE reuptake
Antidepressant
Side effects: high BP, stimulant effects, sedation, nausea

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6
Q

Duloxetine

A

SNRI: inhibit 5-HT (serotonin) and NE reuptake
Antidepressant
Side effects: high BP, stimulant effects, sedation, nausea
*also used for diabetic peripheral neuropathy

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7
Q

Imipramine

A

TCA (Antidepressant): block reuptake of 5-HT and NE
Tertiary amine: SERT>NET
Side effects: sedation, hypotension, arrythmias; more anticholinergic effects (tachycardia, urinary retention, dry mouth) than 2ndary amines

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8
Q

Amitriptyline

A

TCA (Antidepressant): block reuptake of 5-HT and NE
Tertiary amine: SERT>NET
Side effects: sedation, hypotension, arrythmias; more anticholinergic effects (tachycardia, urinary retention, dry mouth) than 2ndary amines

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9
Q

Desipramine

A

TCA (Antidepressant): block reuptake of 5-HT and NE
Secondary amine: NET>SERT
Side effects: sedation, hypotension, arrythmias; fewer anticholinergic effects (tachycardia, urinary retention, dry mouth) than tertiary amines

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10
Q

Nortriptyline

A

TCA (Antidepressant): block reuptake of 5-HT and NE
Secondary amine: NET>SERT
Side effects: sedation, hypotension, arrythmias; fewer anticholinergic effects (tachycardia, urinary retention, dry mouth) than tertiary amines

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11
Q

-iptyline or -ipramine

A

TCA (Antidepressant): block reuptake of 5-HT and NE

Side effects: sedation, hypotension, arrythmias; anticholinergic effects (tachycardia, urinary retention, dry mouth)

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12
Q

Tranylcypromine

A

MAOI (antidepressant)
Mech: nonselective inhibition of MAO; increases levels of dopamine, serotonin, and NE
Risk: hypertensive crisis (interaction with tyramine from wine, cheese, fermented foods)
Contra: SSRIs, TCAs

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13
Q

Phenelzine

A

MAOI (antidepressant)
Mech: nonselective inhibition of MAO; increases levels of dopamine, serotonin, and NE
Risk: hypertensive crisis (interaction with tyramine from wine, cheese, fermented foods)
Contra: SSRIs, TCAs

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14
Q

Isocarboxazide

A

MAOI (antidepressant)
Mech: nonselective inhibition of MAO; increases levels of dopamine, serotonin, and NE
Risk: hypertensive crisis (interaction with tyramine from wine, cheese, fermented foods)
Contra: SSRIs, TCAs, bipolar (can induce mania)

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15
Q

Bupropion

A

antidepressant
Mech: unknown, increases dopamine and NE
No sexual side effects
Side effects: stimulant, headache, seizure in bulimic patients

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16
Q

Mirtazapine

A

Antidepressant
Mech: alpha-2 antagonist; increase release of 5-HT and NE; 5-HT(2) and 5-HT(3) receptor antiagonist
Side effects: sedation, increased appetite, weight gain

17
Q

Trazodone

A

Antidepressant
Mech: blocks 5-HT(2) and alpha-1 receptor
Used for insomnia bc high doses are needed for AD effects
Side effects: sedation, nausea, priaprism, postural hypotension

18
Q

Lithium

A

Bipolar meds: Maintenance
Mech: unknown
Mood stabilizer; blocks relapse and acute manic events
Side effects (LMNOP): Movement (tremor), Nephrogenic diabetes insipidusm, hypOthydroidism, Pregnancy problems

19
Q

Busiprone

A 
Bipolar meds
Mech: stimulates 5-HT(1A) receptors
Used for generalized anxiety disorder
Takes 1-2 weeks to take effect
No sedation, addition, or tolerance
No interaction with alcohol
20
Q

Selegiline

A

MAOI (antidepressant)
Mech: SELECTIVE inhibition of MAO-B; increases levels of dopamine, serotonin, and NE
Risk: hypertensive crisis (interaction with tyramine from wine, cheese, fermented foods)
Contra: SSRIs, TCAs

21
Q

Valporate AKA Valproic acid

A

Bipolar meds: Maintenance

Mood stabilizer

22
Q

Carbamazepine

A

Bipolar meds: Maintenance

Mood stabilizer

23
Q

Lamotrigine

A

Bipolar meds: Maintenance

Mood stabilizer

24
Q

Olanzapine

A

Bipolar meds: Maintenance
Mood stabilizer
Antipsychotic

25
Q

Chloropromazine

A

Bipolar meds: Manic phase

Antipsychotic

26
Q

Haloperidol

A

Bipolar meds: Manic phase

Antipsychotic

27
Q

Risperidone

A

Bipolar meds: Manic phase

Antipsychotic

Neuro Midterm (10 decks)

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