pharma 4.4 Derma quiz Flashcards

0
Q

Plasma testosterone in normal active women is produced from

A

Ovaries and adrenal cortex

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1
Q

Daily production of endogenous testosterone in normal male adult

A

8mg

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2
Q

Major active androgen in normal adult male

A

DHT

Dihydrotestosterone

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3
Q

DHeA from the adrenal cortex has some beneficial effects clinically in which dses?

A

Atherosclerosis

SLE

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4
Q

Effect of androgen on HDL cholesterol level

A

Decreased

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5
Q

DOC for koliocytosis with multiple small vesiculo nodular lesions at penile shaft

A

Imiquinod

Immunomodulator

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6
Q

Does not produce ACD (?) as an ADR

A

Isotretinoin

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7
Q

Biologic agent in Psoriasis Tx that binds to IL12 and IL 23

A

Ustekinumab

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8
Q

Used as humectant keratolytic in 20% conc in icthyosis or keratosis pilaris

A

Urea

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9
Q

Highest level of androgenic/anabolic activity of testosterone

A

Oxandolone

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10
Q

ADRs of adult androgen replacement tx in men

A

Gynecomastia

Azoospermia

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11
Q

HCC is common in prolonged use of

A

Androgen

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12
Q

DOC for adenocarcinoma of prostate before Sx

A

Flutamide

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13
Q

Finasteride os DOC for

A

Female hirsutism
BPH
Adenocarcinoma of the prostate

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14
Q

DOC of immunologic contact dermatitis

Hypersensitivity type 1

A

Anti H1

Topical steroid

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15
Q

Ectoparasite drug for pediculosis only

Not for scabies

A

Malathione

Benzoyl alcohol

16
Q

Drospirenone + ethinyl estradiol is a combination drug for this dermal disorder

A

FEMALE acne

17
Q

DOC vitamin preparations for plaque-like lesions on palms and soles when hydrocortisone is unresponsive

A

Calcipotriene

18
Q

What level of efficacy does hydrocortisone belong to?

A

Medium efficacy

19
Q

The topical steroid with the highest efficacy? Availability?

A

Clobetasol

20
Q

Topical DOC for Actinic Keratosis

A

5-FU

21
Q

DOc for condyloma acuminata

A

Imiquinod

22
Q

Indication of ustekinumab

A

Psoriasis

23
Q

Ecamsule is what kind of drug

A

Sunblock

24
Q

MOA: inhibition of isoleucyl t-RNA synthetase

A

Mupirocin (bactroban)

25
Q

Useful in genital warts as destructive agent

A

Sinecatechins

26
Q

Shampoo for scalp psoriasis

A

Coal tar

27
Q

Hypersensitivity type with washer woman’s hands of laundry woman

A

Hypersensitivity type 4

28
Q

Topical DOC for washer woman’s hands of laundry woman

A

Halobetasol

29
Q

Photochemo tx with methoxsalen indicated in

A

Plaque psoriasis

30
Q

DOc for depigmented skin of vitiligo

A

Trioxsalen

31
Q

Destructive agent from green tea leaves indic as topical tc for perianal warts

A

Sinecatechins

32
Q

Contact urticaria is IgG mediated belong to what type of hypersensitivity reaction

A

Type 1

33
Q

Ciclopirox olamine is DOc for P. Orbiculare

What type of drug is this?

A

Anti fungal

34
Q

Oral antibiotic CI inpregnancy due to carcinogenic and teratogenic effects

A

Metronidazole

35
Q

MOA: inhibition of ornithine decarboxylase

A

Eflornithine

36
Q

Does not produce acid as an ADR

A

Urea