Pharmacodynamics I Flashcards
T/F: Concentratration at effector site is determined by both pharmacokinetics and pharmacodynamics.
True
What type of bond would cause an irreversible change to a drug?
A. Hydrogen bond
B. Ionic bond
C. Covalent bond
D. Hydrophobic interactions
C. Covalent
T/F: Most drug-receptor interactions involve strong often irreversible interactions
False, most drug-receptor interactions involve, weak and reversible interactions. This is vital to avoiding drug toxicity
Which of the following would terminate the effect of a covalent drug binding to a receptor?
A. Drug dissociation from receptor
B. Taking another drug that has the opposite effect
C. Time
D. Destruction of D-R complex
D. Destruction of D-R complex