Pituitary Pathophysiology Flashcards
Excess ACTH
Cushing’s Syndrome
Presentation of Cushing’s Syndrome
Weight gain Hypertension Red striae Acne Proximal myopathy Bruising Diabetes
Diagnosis of Cushing’s Syndrome
Dextrose suppression test
Measure ACTH
Treatment of Cushing’s Syndrome
Remove tumor
Block production
Adrenalectomy
Excess GH
Acromegaly
Presentation of Acromegaly
Coarse features
Large hands and feet
Hyperglycemia
Hypertension
Diagnosis of Acromegaly
High IGF-1
Treatment of Acromegaly
Surgery
Somatostatin
Pegvisomant
Prolactinoma presentation
Excess prolactin
Galactorrhea
Amenorrhea
Prolactinoma Diagnosis
Measure prolactin
Prolactinoma Treatment
Bromocriptine
Cabergoline
SIADH Presentation
Excess ADH
Hyponatremia
SIADH Diagnosis
Euvolemic hyponatremia
SIADH Treatment
Water restriction
Conivaptan
GH Deficiency Presentation
Short stature
Failure to grow