Pituitary Pathophysiology Flashcards

1
Q

Excess ACTH

A

Cushing’s Syndrome

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2
Q

Presentation of Cushing’s Syndrome

A
Weight gain
Hypertension
Red striae
Acne
Proximal myopathy
Bruising
Diabetes
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3
Q

Diagnosis of Cushing’s Syndrome

A

Dextrose suppression test

Measure ACTH

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4
Q

Treatment of Cushing’s Syndrome

A

Remove tumor
Block production
Adrenalectomy

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5
Q

Excess GH

A

Acromegaly

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6
Q

Presentation of Acromegaly

A

Coarse features
Large hands and feet
Hyperglycemia
Hypertension

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7
Q

Diagnosis of Acromegaly

A

High IGF-1

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8
Q

Treatment of Acromegaly

A

Surgery
Somatostatin
Pegvisomant

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9
Q

Prolactinoma presentation

A

Excess prolactin
Galactorrhea
Amenorrhea

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10
Q

Prolactinoma Diagnosis

A

Measure prolactin

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11
Q

Prolactinoma Treatment

A

Bromocriptine

Cabergoline

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12
Q

SIADH Presentation

A

Excess ADH

Hyponatremia

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13
Q

SIADH Diagnosis

A

Euvolemic hyponatremia

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14
Q

SIADH Treatment

A

Water restriction

Conivaptan

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15
Q

GH Deficiency Presentation

A

Short stature

Failure to grow

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16
Q

GH Deficiency Diagnosis

A

Arginine-GHRH
or
Hypoglycemia stimulation of GH

17
Q

GH Deficiency Treatment

A

Synthetic growth hormone

18
Q

ACTH Deficiency Presentation

A

Lassitude
Fatigue
Postural hypotension

19
Q

ACTH Deficiency Diagnosis

A

ACTH stimulation test (of adrenals)

20
Q

ACTH Deficiency Treatment

A

Glucocorticoids

21
Q

TSH Deficiency Presentation

A

Classical hypothyroidism

22
Q

TSH Deficiency Diagnosis

A

Low TSH with low T4 levels

23
Q

TSH Deficiency Treatment

A

Levothyroxine