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Endocrine > Pituitary Physiology > Flashcards

Pituitary Physiology Flashcards

1
Q

The failure of ___ of the pituitary to close during development may cause tumors

A

Rathke’s Pouch

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2
Q

What are the two activating TFs of the pituitary gland

A

Prop-1, Pit-1

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3
Q

TSH, LH, and FSH are ___ hormones and share the same _ subunit

A

glycoprotein; alpha

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4
Q

ACTH comes from the large molecule __

A

POMC

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5
Q

Both __ and __ can activate the prolactin receptor

A

GH; prolactin

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6
Q

GH stimulates secretion of __ which is responsible for ___

A

IGF-1; anabolic growth

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7
Q

TSH stimulates

A

thyroid hormone release

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8
Q

ACTH stimulates

A

adrenal cortex steroid release

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9
Q

Loss of end organ feedback results in ___ of the pituitary

A

hypertrophy

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10
Q

Circadian rhythms occur __ and ultradian rhythms are ___ style

A

daily; burst

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11
Q

ACTH stimulates __ production

A

cortisol

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12
Q

2 extra adrenal functions of ACTH

A

stimulate lipolysis and increase skin pigmentation

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13
Q

ACTH production has a ___ pattern and peaks before __

A

diurnal; awakening

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14
Q

__ inhibits ACTH release and ___ stimulates it

A

cortisol; CRH

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15
Q

GH stimulated by ___, inhibited by

A

GHRH, IGF-1, GH

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16
Q

Non-hormonal stimulators of GnRH

A

Hypoglycemia, protein, exercise

17
Q

__ inhibits GnRH action as well as __ and __ in pituitary

A

somatostatin; TSH; PRL

18
Q

__ is used to measure GH effect on the tissue

A

IGF-1

19
Q

NT inhibitor of prolactin

A

Dopamine

20
Q

Prolactin is not a closed loop- exogenous stimulators include

A

breast stimulation, stress, estrogen, sleep

21
Q

Prolactin negatively stimulates __ and __ via __

A

FSH/LH; hypothalamus

22
Q

__ from the hypothalamus stimulates TSH and can co-stimulate ___

A

TRH; prolactin

23
Q

T3 decreases ___ receptors on the ___ so __ decreases

A

TRH; anterior pituitary; TSH

24
Q

The only hypothalamus input that is inhibitory is on

A

prolactin via dopamine

25
Q

Feedback from hormones on axis is negative except for __ during __

A

estrogen during ovulation

Endocrine (25 decks)

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