Post Transplant Issues Flashcards
Most common post transplant infection
Streptococcus pneumoniae
Most common viral infection post transplant
cmv
CMV treatments
Ganciclovir, foscarnet, calacyclovir
Live virus vaccine
MMR and zoster
in RIC grafts, what is an indicator of graft rejection?
day +28, high number of recipient t cells.
SIde effects of DLI
GVHD and marrow aplasia
Neutropenic fever organism
Gram +
Most commo locations for infections in the neutropenic period
central line and oral mucosa
Common infections in the pre engraftment neutropenic period
gram + and gram -, HSV, Aspergillus, candida
Preemptive therapy and tx of CMV-seronegative recipients w/ seropositive donors
ganciclovir
Minor ABO incompatability
Donor is O; donor has antibodies towards recipient
Major ABO incompatability
Recipient is O; recipient has antibodies toward donor
what is the primary indicator for HSCT outcomes?
absolute lymphocyte count (>500/mm3)
Carmustine and cytoxan are ___ emesis risk
high
Busulfan, ara-c, melphalan are ___ emesis risk
medium