Powder technology Flashcards

1
Q

Interpaticular forces

A
  • Friction
  • Mechanical interlocking of particles
  • Cohensive forces
  • Liquid bridges
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2
Q

Friction

A
  • Surface properties between particle and particle wall
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3
Q

Mechanical interlocking

A
  • Size of particle (dependent)

- Position of the particle

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4
Q

Cohesive forces

A
  • Van der walls

- Electrostatic (particle charge interactions, electrical potential contact difference)

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5
Q

Liquid bridges

A

Liquid between particles that cause and increase in interaction between solids.

  • Capillary forces
  • Surface tension
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6
Q

Angle of response

A
  • Base of dimeter with a fixed diameter and funnel 2-4nm
  • Angle >50 not good flow
  • <50 good flow
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7
Q

Tap density

A
  • Simple method to predict flow characteristics
  • Indication of bulk size/density/size and shape and surface area.
  • low compression index and low hanser ratio give better flow
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8
Q

Flow through an orfice

A
  • Direct method to measure flow properties

- No general scale of flowability

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9
Q

Particle size >250nm

A
  • Good flow
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10
Q

Particle size <100nm

A
  • Flow problems
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11
Q

Properties of formulation additives

A
  • Small
  • Hard
  • Unreactive
  • Insoluble
  • Keep particles separated
  • Improve flow
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12
Q

Modolling powder flow

A
  • Size
  • Density
  • Moisture content
  • Shape
  • Packaging
  • Formulation additives
  • Equipment method used
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13
Q

Ways to measure powder technology

A

1) Sheer cell measurement
2) Angle of response
3) Tap density
4) flow through an orifice

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