PPt Evolution And Population Genetics (Ex 1) Flashcards

1
Q

Defining a Population

A
  1. A group of individuals of the same species living in the same place at the same time
  2. Evolution acts on POPULATIONS, not on individuals
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2
Q

Evolution

A
  1. Change in the inherited traits of a population of organisms from generation to generation
  2. Natural Variation, Reproduction, Selection, Genetic Drift, Gene Flow
  3. Can be RANDOM (genetic drift)
  4. Can be NON-RANDOM (selection)
  5. HAS NO GOAL—mutations occur by chance, not when they’re “needed”
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3
Q

Micro-evolution

A

Studies changes within a population (single species)

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4
Q

Macro-evolution

A

Studies changes that divide a population (speciation)

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5
Q

Hardy-Weinberg—Test of Evolution

A
  1. Wilhelm Weinberg and G.H. Hardy
  2. Null model-“evolution isn’t happening here”
  3. Allows us to detect changes in gene flow within a population (“reject null hypothesis”)
  4. Test observations to see whether evolution is occurring
  5. If evolution IS occurring expect changes in allelic frequencies
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6
Q

Hardy-Weinberg 5 Postulates/assumptions

A
  1. Large Population
  2. Isolated Population
  3. No net mutations
  4. Random mating
  5. No natural selection
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7
Q

Hardy-Weinberg Equilibrium

A

Q^2+2pq+p^2 = 1
2pq=Aa
Q^2=aa
P^2=AA

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8
Q

Gene

A

A gene is a unit of heredity information that consists of a specific nucleotide sequence. A gene codes for a certain character (usually a protein)

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9
Q

Allele

A

An allele is an alternative form of a gene that codes for a certain variety of that character

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10
Q

Phenotype

A

A phenotype is the set of observable characteristics of an individual resulting from the interaction of its genotype with the environment

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11
Q

Genotype

A

A genotype is the alleles of a gene or genes present in a given individual

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12
Q

Genotype vs Phenotype

A

GENOTYPE
1. The genotype is an organism’s genetic information
2. BB homozygous dominant, Bb heterozygous, bb homozygous recessive
PHENOTYPE
1. The phenotype is the set of observable physical traits
2. Purple, purple, white

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13
Q

Rabbits—Allele,Genotype,Phenotype

A

A: C, G: CC, P:Wild type: Brown fur
A: c^ch, G: c^chc^ch, P:Chinchilla: Black-tipped white fur
A:c^h, G:c^hc^h, P:Himalayan: White fur with black paws, nose, ears, tail
A:c, G:cc, P:Albino:White fur

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14
Q

Punnett Squares

A

R=Red r=yellow individual 1 = Rr Individual 2=rr
Rr,Rr,rr,rr

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15
Q

Genotypes & Phenotypes

A

Genotype:
1. Genetic constitution of a cell
2. Allele Composition
3. Trait we cannot see
Phenotype
1. Trait we can see

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16
Q

Alleles (Roses)

A

R=Red Petals
r=White Petals
Rr x Rr
RR,Rr,rR,rr
Dominant Allele = R = Red Petals
Recessive Allele = r = White Petals
Homozygous Dominant = Red
Homozygous Recessive = White
Heterozygous = Rr = Red

17
Q

Calculating Allele Frequency

A
  1. P+q=1
  2. P= frequency of Dominant allele
  3. q = frequency of Recessive allele
18
Q

Calculating Genotype Frequency

A
  1. P^2 +2pq +q^2 = 1
  2. P^2 = frequency of homozygous dominant type
  3. 2pq = frequency of heterozygous type
  4. Q^2 = frequency of homozygous recessive type
19
Q

Hardy-Weinberg Practice
If the black fur gene is dominant BB, and the white fur gene is recessive bb, and a grey fur gene is Bb: When there are 122 black mice, 34 grey mice, and 67 white mice, What is q?

A

B = frequency p
b = frequency q
1 = p^2 + 2pq + q^2
Total allele = 122+122+34+34+67+67=446
B = (122x2) + 34 = 278
b = (67x2) + 34 = 168
q = 168/446 = 0.3766

20
Q

Hardy-Weinberg extra info

A
  1. A population is not evolving and is at equilibrium if HW equation = 1
  2. If our observed allelic frequencies match our expected allelic frequencies, the population is not evolving
21
Q

Darwin Requirements

A
  1. Variation: “individuals within species are variable”
  2. Inheritance: “some of these variations are passed on to offspring”
  3. Differential survival: “in every generation, more offspring are produced than can survive”
  4. Extinction: “the survival and reproduction of individuals is not random. Individuals who survive and reproduce are those with the most favorable variation…”
22
Q

***Hardy-Weinberg Requirements

A
  1. No mutation
  2. No natural selection (no phenotypes outperform others in the population’s environmental conditions)
  3. Extremely large population size (no genetic drift)
  4. No gene flow
  5. Random mating (all individuals have an equal chance of passing on their alleles, no individual more likely to mate based on their alleles/phenotype)
23
Q

Hardy-Weinberg Practice Hypothesis (mice problem)

A

Hypothesis: This population is evolving
Null hypothesis: This population is in HW equilibrium and is not evolving