Flashcards in Pregnancy and Breastfeeding medications CI Deck (4):
what sorts of drugs are LESS likely to cross from the maternal blood to the baby via breastmilk?
drugs that are highly bound to plasma proteins in the mother's blood will be less able to transfer to milk
what are some general practice points for prescribing medications to lactating women?
1. determine if the drug is absorbed via GIT as may be poorly absorbed by infant's GIT
2. compare amount absorbed to a paediatric dose
3. choose shorter half life drugs!
4. choose drugs with high protein binding!
5. be careful of medications applied to the nipple
a breastfeeding mother needs to take a radioactive compound/drug (e.g. for cancer). what might you advise her in terms of breastfeeding?
wait at least 4-5 half lives before breastfeeding. After 5 half-lives, 98% of the drug will be eliminated.