Prostate Flashcards

1
Q

High consumption of _________fats , such as _________ or _______ can cause prostate cancer.

A

Dietary fats, alpha linoleic acid or polycyclic aromatic hydrocarbons

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2
Q

Consumption of isoflavonoid genistein prevents what cancer?

A

Prostate

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3
Q

(cauliflower, cabbage, kale kind) Cruciferous vegetables with_________ is a protective factor for prostate cancer

A

Isothiocyanate sulforaphane

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4
Q

_______ found in tamotoes is a protective factor for prostate cancer

A

Lycopene

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5
Q

Is inhibitors of cholesterol biosynthesis like statin is it a protective factor for prostate cancer. True or False

A

True

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6
Q

_________ are the predominant therapies?

A

5 alpha reductase inhibitors

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7
Q

Prostate cancer occur in _______ zone?

A

Peripheral

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8
Q

PSA is increased in?

A

Prostate cancer, prostatitis, BPH

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9
Q

PSA levels are undetectable after about ___________ weeks if prostate has been completely removed.

A

6

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10
Q

95% of the prostate cancers are transitional cell tumors. True / false?

A

False, Adenocarcinoma

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11
Q

Second line screening tests for prostate cancer?

A

4K score
Prostate health index

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12
Q

CT> MRI in prostate cancer? True or false

A

True

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13
Q

T1 is inapparent tumor? True or false

A

True

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14
Q

T3- invades adjacent structures? True or False

A

False, T4 invades adjacent structures
T3- extends through prostate capsule and may invade seminal vesicles

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15
Q

T2 tumor is confined within prostate?true or false

A

True

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16
Q

After radicle surgery to removal all prostrate tissue, PSA should be undetectable in the blood within_____ weeks.

A

6

17
Q

After radiation therapy PSA becomes undetectable? True or False?

A

False, PSA is still detectable after radiation therapy because the remaining non-malignant elements of the gland continue to produce PSA even if all cancer cells have been eliminated.

18
Q

Do you preserve external spincter in radical prostatectomy? True or false?

A

True

19
Q

Do you spare Autonomic nerves in radicle prostectomy? True or False?

A

True

20
Q

Radical prostatectomy gives a life expectancy of 2 yrs? True or False

A

False, it gives a life expectancy of 10 yrs or more

21
Q

Complications of radical prostatectomy are?

A

Erectile dysfunction & incontinence

22
Q

Erectile function never returns after radical prostatectomy? True or False?

A

False, erectile function begins to return 6 months after surgery if neurovascular tissue has been preserved.

23
Q

Safe administration doses_____ and resulted in higher local control rates and fewer side effects.

A

> 80gy

24
Q

This is direct implantation of radioactive sources into the prostate.

A

Brachytherapy

25
Q

____________is the treatment recommended to patients with cancers of low aggressiveness.

A

Active surveillance

26
Q

What are the testosterone lowering agents given for prostate cancer?

A

GnRH agonists/ antagonists - leuprolide acetates and goserlin acetate
Pure GnRH antagonists - Degarelix or relugilix
17, 20-lyase inhibitors
CYP 17 inhibitors
Estrogen such as diethylstilbestrol