PROTEIN METABOLISM Flashcards

1
Q

protein digestion starts where?

A

stomach

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2
Q

produced in the pancreas

A

pancreatic juice

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3
Q

is the breakdown & re-synthesis
of body protein

A

protein turnover

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4
Q

what amino acid is most important metabolically

A

glutamate

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5
Q

Escapes in large amounts from dead or dying liver tissue.
Measured in blood samples for diagnostic purposes.

A

alanine aminotransferase

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6
Q

Also escapes in large amounts from dead or dying heart tissues & enters bloodstream.
Measured in blood for diagnosing myocardial infarction.

A

aspartate aminotransferase

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7
Q

will reversibly convert
glutamate to α-ketoglutarate
and α-ketoglutarate to glutamate.

A

Glutamate dehydrogenase

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8
Q

converting glutamate to α-ketoglutarate is an easily shifted equilibrium reaction.

A

Oxidative deamination

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9
Q

are toxic compounds in urea cycle

A

Ammonium salts

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10
Q

building up favors the synthesis of excessive amounts of glutamate, decreasing the Krebs cycle intermediate

A

Ammonium ions

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11
Q

the urea cycle are NH3, CO2 and aspartic acid and ATP.

A

input

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12
Q

The ___ are urea, ADP and fumaric acid.

A

outputs

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13
Q

Spiders excrete _______, 5 nitrogen atoms in a small molecule.

A

guanine

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14
Q

Aquatic species excrete free _____through gills.

A

ammonia

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15
Q

Terrestrial critters produce ____- very soluble - still needs water for removal via kidneys.

A

urea

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16
Q

Defective phenylalanine hydroxylase –
phenylalanine accumulates in body.
Phenylalanine is transaminated to phenylpyruvate.

A

Phenylketonuria

17
Q

leads to severe mental retardation in infants.

A

Phenylketonuria (PKU)

18
Q

a biochemical reaction that involves the
interchange of the amino group of an a-amino acid

A

transamination reaction

19
Q

is a biochemical reaction in which an a-amino acid is converted into an a-keto acid

A

oxidative deamination
reaction

20
Q

cyclic biochemical pathway in
which urea is produced, for excretion

A

urea cycle

21
Q

amino acid that can be
converted into glucose through
gluconeogenesis.

A

KETOGENIC

22
Q

are converted into ketone bodies.

A

glucogenic

23
Q

s a rare (1:185,000), autosomal recessive disorder in which there is a
partial or complete deficiency in branched-chain α-keto acid dehydrogenase

A

Maple syrup urine disease (MSUD)

24
Q

refers to a group of conditions in which a defect in tyrosine metabolism results in a deficiency in the
production of melanin

A

albinism