Protein Structure Flashcards
1
Q
alpha helix info
A
Right handed 3.6 residues per turn H-bond between i and i+4 R groups project out of helix transmembrane protein have 7 transmembrane helices
2
Q
Beta sheet
A
Parallel or anti-parallel
R groups above and below sheet
3
Q
6 Supersecondary structures
A
a-a hairpin Four a-helix bundle beta hairpin Greek key motif beta meander Zinc finger
4
Q
aa hairpin
A
Amphipathic, with hydrophobic groups inside
5
Q
b-a-b hairpin
A
Rossman fold
Found in lactate dehydrogenase
6
Q
Greek key motif
A
Forms b-sandwich, basis for immunoglobulin fold
7
Q
b-meander
A
Forms b-barrels, which exist in porins
8
Q
Zinc finger
A
Zn2+ ion stabilizes fold
Facilitates DNA binding, eg. HATs
