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CLINICAL CHEMISTRY > PROTEINS > Flashcards

PROTEINS Flashcards

1
Q

Protein from greek word …

A

Proteis meaning “first rank of importance”

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2
Q

Proteins are synthesized in the …

A

Liver by the hepatocytes

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3
Q

Proteins are synthesized in the liver except

A

Immunoglobulins

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4
Q

Proteins provide how many percent of total daily body energy requirements

A

12-20%

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5
Q

Proteins are how many percent of the cell’s dry weight

A

50-70%

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6
Q

It is the linear sequence of the amino acid

A

Primary structure

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7
Q

It determines the identity of protein, and molecular structure …

A

Primary structure

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8
Q

It involves the winding of the polypeptide chain

A

Secondary structure

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9
Q

It is the actual 3-dimensional configuration; the folding pattern of the protein

A

Tertiary structure

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10
Q

Responsible for many of the physical and chemical properties of the proteins

A

Tertiary structure

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11
Q

It is the association of 2 or more polypeptide chains to form a functional protein molecule

A

Quaternary structure

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12
Q

They contain peptide chains which on hydrolysis yield only amino acids

A

Simple proteins

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13
Q

Composed of protein and a non-protein moiety

A

Conjugated proteins

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14
Q

It is when a protein catabolism exceeds anabolism

A

Negative nitrogen balance

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15
Q

It is when a protein anabolism exceeds catabolism

A

Positive nitrogen balance

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16
Q

It migrates ahead of albumin

A

Prealbumin (transthyretin)

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17
Q

Prealbumin transports …

A

T4 and Retinol (Vitamin A)

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18
Q

It is the protein with the highest concentration in plasma

A

Albumin

19
Q

A general transport protein

A

Albumin

20
Q

Albumin is a type of what reactant phase

A

Negative acute phase reactant

21
Q

The reference value of Albumin

A

3.5-5.0 g/dL

22
Q

It is a group of proteins consists of a1, a2, B, and Y fractions

A

Globulins

23
Q

It is a major inhibitor of protease activity - prevents self-destruction of tissue

A

a1-antitrypsin

24
Q

It is synthesized initially by the fetal yolk sac and then by the fetal parenchymal cells of the liver

A

a1-fetoprotein

25
Q

Decreased a1-fetoprotein is associated with

A

Down syndrome and Trisomy 18

26
Q

It binds with heme released by the degradation of hemoglobin

A

Hemopexin

27
Q

It binds free hemoglobin by its a-chain

A

Haptoglobin

28
Q

It is a copper-binding a2-glycoprotein that has enzymatic activities

A

Ceruloplasmin

29
Q

It is the largest major nonimmunoglobulin protein in plasma

A

a2-macroglobulin

30
Q

It is found on the surface of most nucleated cells

A

B2-microglobulin

31
Q

It is needed in the production of CD8 cells

A

B2-microglobulin

32
Q

It transports iron to its storage sites

A

Transferrin (siderophilin)

33
Q

It is synthesized in the plasma cells

A

Immunoglobulins

34
Q

It binds with proteins and lipids forming LDL, HDL, VLDL

A

Lipoprotein

35
Q

It is one of the largest proteins in the blood and most abundant of the coagulation factor

A

Fibrinogen

36
Q

It is one of the natural defence mechanisms that protects the human body from infection

A

Complement

37
Q

It is a member of the pentraxin family and a neonatal screening for sepsis

A

C-reactive protein

38
Q

It is a potential nephrotoxic

A

Myoglobin

39
Q

It binds to the thin filaments of cardiac muscles

A

Troponins

40
Q

These are regulators of actin and myosin

A

Troponins

41
Q

It is only found in the myocardium

A

Troponin I

42
Q

It is an early indicator of glomerular dysfunction

A

Microalbuminuria

43
Q

It

A

CLINICAL CHEMISTRY (6 decks)

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