Pyruvate dehydrogenation and TCA cycle

Question 1

What is pyruvate converted to in the absence of oxygen?

Answer 1

Lactate

Question 2

What is pyruvate converted to aerobically

Answer 2

Acetyl CoA

Question 3

What converts pyruvate to Acetyl CoA? Is it a oxidative one reductive reaction?

Answer 3

Pyruvate Dehydrogenase Complex. Oxidative. NAD+ becomes NADH H+

Question 4

Give an overview of TCA cycle

Answer 4

2 carbon unit from Acetyl CoA is combined with oxalacetate to form citrate. Citrate is decarboxylated twice and yields2 CO2s, 3 NADH, 1 FADH2 and 1 GTP

Question 5

Where does the TCA cycle occur?

Answer 5

Mitochondrial matrix

Question 6

Which is the one enzyme located on the inner mitochondrial membrane?

Answer 6

Succinct dehydrogenase. Converts succinctness and FAD into fumarate and FADH2

Question 7

How many FADH2 and NADH, H+ does glycolysis, pyruvate dehydrogenase and TCA cycle produce all together

Answer 7

10 NADH,H+

2 FADH2