Questions Flashcards
Cytochalsin
Prevents polymerization
Phalloidin
Prevents depolymerization
Taxol
Caps + end of MT
Colchicine
Prevents polymerization of MT’s
Vinblasine
Prevents Polymerization of MT’s
Keratin
Epithelia
GFAP
Glia
Vimentin
CT, Mesechyme
Desmin
Skeletal Muscle
Neurofilaments
Neurons
DNA condensation (small to large)
Helix => Nucleosome => solenoid => chromosome
What does cyclin do?
regulates cell cycle. interact with cyclin-dependent kinases .
Cyclins bound to ubiquitin tags for destruction by proteosomes
What happens in G1, S, G2
G1 - growth of cell
S - DNA replication
G2 - growth and replication of organelles
Checkpoints of cell cycle (what they check for)
G1
G2
M
G1 - looks for envirnmental signals
G2 - cell big enough? DNA replicated?
M - are chromosomes lined up
Role of p53
actives p21 when DNA is damaged