Quiz #1 Flashcards

1
Q

what is the cerebrum made of?

A
frontal lobe
parietal lobe
occipital lobe
temporal lobes
subcortical structures
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what purpose does the frontal lobe serve?

A

voluntary movement and language production by the motor strip, the supplemental motor area, and Broca’s area
executes goal-oriented activity by the prefrontal cortex [PFC]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what purpose does the parietal lobe serve?

A

receives and identifies sensory info. [touch, pressure, pain and temp.] by primary sensory area
able to form concepts and abstract ideas [i.e. language]
right and left orientation, body awareness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what purpose does the occipital lobe serve?

A

interprets visual images
visual association
visual memories
involved w language formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what purpose do the temporal lobes serve?

A

concerned w/ sensory experience
role in memory processing and emotion
contain hippocampus, which interacts w/ the prefrontal area in memory and learning
- the amygdala, also found here, plays major role in memory and in processing fear and anxiety

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what [1] is and [2] makes up the limbic system?

A

made up by the amygdala, hippocampus, hypothalamus, and thalamus
it may also be referred to as the “emotional brain”
it appears to house the emotional association areas and is implicated in what is termed the four “F’s”: fighting, fleeing, feeding, and fucking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what purpose do the subcortical structures serve?

A

made up of 4 subcortical basal ganglia that makes up gray matter nuclei
allows for smooth integration of emotions, thoughts, and physical movement
role in motor responses via the extrapyramidaal motor system
- relies on dopamine to maintain muscle tone and motor stability

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what purpose does the thalamus serve?

A

the major sensory relay station to the cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what purpose does the hypothalamus serve?

A

maintains homeostasis
regulates temp., B.P., sexual drive, hunger, thirst, and circadian rhythms
hypothalamic neurohormones, or releasing hormones, direct the secretion of hormones from the anterior pituitary gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what purpose does the cerebellum serve?

A

primarily involved in balance and smooth muscle movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what [1] are neurons and [2] what purpose do they serve in the brain?

A

they’re able to conduct an electrical impulse from one end of the cell to the other, neurotransmission, converted at synapes where neurotransmitters are released, electrical signals are elicited on other side of synapse
- this is how info. processing in the brain occurs
once the electrical impulse reaches the end of a neuron, the neurotransmitter is released from the axon terminal
- the transmitter crosses the synapse to an adjacent postsynaptic neuron, where it attaches to specialized receptors on the cell surface and either inhibits or excites the postsynaptic neuron
the transmitter then separates from the receptor and is destroyed or reuptaked into the cell from which they were released

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what are the [1] major groups of neurotransmitters and [2] examples of each ?

A

monoamines [i.e. dopamine, norepi., serotonin, histamine]
amino acids [i.e. GABA, glutamate]
peptides [i.e. neurotensin]
cholinergics [i.e. Ach]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what are the [1] functions and [2] clinical revelance of dopamine?

A
it is an excitatory neurotransmitter
fx:
fine muscle movement
integration of emotions and thoughts 
decision-making
stimulates hypothalamus to release hormones
stimulates the heart
c.r.:
increases schizophrenia, mania
decreases parkinson's disease, depression
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what are the [1] functions and [2] clinical revelance of norepi.?

A
it is an excitatory neurotransmitter
fx: 
mood [along w/ serotonin]
attention and arousal
stimulates sympathetic branch of autonomic nervous sytem for "fight or flight" in response to stress
c.r.: 
increases mania, anxiety, schizophrenia
decreases depression
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what are the [1] functions and [2] clinical revelance of serotonin?

A
it is an excitatory neurotransmitter
fx: 
mood [along w/ norepi.]
sleep regulation
hunger
pain perception
aggression
hormonal activity
c.r.: 
increases anxiety [w/ high levels]
dereases depression
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what are the [1] functions and [2] clinical revelance of histamine?

A
it is an excitatory neurotransmitter
fx: 
alertness
inflammatory response
stimulates gastric secretion 
c.r.: 
increases hyperactivity, compulsivity, suicidal depression
decreases sedation, weight gain, hypotension
17
Q

what are the [1] functions and [2] clinical revelance of GABA?

A
it is an inhibitory neurotransmitter 
fx: 
reduces anxiety, excitation, aggression
may play a role in pain perception
anticonvulsant and muscle-relaxing properties
c.r.: 
decreases mania, anxiety, schizophrenia
18
Q

what are the [1] functions and [2] clinical revelance of Ach?

A
it is an excitatory neurotransmitter
fx: 
plays a role in learning memory
regulates mood: mania, sexual aggression
affects sexual ad aggressive behavior
stimulates parasympathetic nervous system 
balances dopamine 
c.r.: 
increases depression
decreases: Alzeimer's disease, Huntingdon's chorea, Parkinson's disease
19
Q

what is extrapyramidal symptoms [EPS]?

A

a kind of movement disturbance that occurs when antipsychotic drugs, to varying degrees, block or antagonize receptors, specifically the D2 receptors in the basal ganglia
- tardive dyskinesia is another irregular movement that can occur

20
Q

standard antipsychotic drugs

A

or dopamine receptor antagonists [DRA’s]
bind to dopamine [D2] receptors and reduce dopamine transmission
adverse effects: D2 blockage > extrapyramidal side effects [i.e. dystonia, akathisia, tardive dyskinesia, drug-induced parkinsonism, neuroleptic malignant syndrome], Ach blockage > blurred vsion, dry mouth, constipation, urinary hesitancy
types: low-potency [i.e. lorazepam or ativan], high-potency [i.e. fluphenzine [prolixin, haloperidol or haldol]

21
Q

atypical antipsychotics

A

or serotonin-dopamine antagonists [SDA’s]
higher ratio of serotonin type 2 t D2 receptor blockade causes fewer motor S.E.’s, targets + and - sx.’s of schizo.
types: clozapine, olanzapine, risperidone, quetiapine, ziprasidone, aripiprazole

22
Q

mood stabilizers

A

types: lithium, anticonvulsants, monoamine oxidase inhibitors, tricyclic antidepressants [TCA’S], selective serotonin reuptake inhibitors [SSRI’s], atypical antidepressants

23
Q

antianxiety

A

types: benzodiazepams, buspar

24
Q

what is pharmacogenomics?

A

refers to the general study of the many different genes that determine drug behavior

25
Q

what is pharmacogenetics?

A

the study of inherited differences in drug metabolism ad response