Quiz Two Flashcards

1
Q

Acidophil

A

Cells with cytoplasmic granules that stain readily with acid dyes

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2
Q

Agonist

A

a substance that can bind to a receptor and act like a native substance resulting in the
normal physiologic response

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3
Q

Anastomosis

A

A communication between two hollow parts, organs or vessels, that are normally
separate

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4
Q

Antagonist

A

a substance that inhibits the normal action of a hormone or native substance.

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5
Q

Androgen

A

Hormones with masculinizing properties

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6
Q

Autocrine communication

A

When a hormone stimulates the same cell from which it is
secreted.

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7
Q

Basophil

A

A group of cells containing granules which stain readily with basic dyes

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8
Q

Bioassay

A

Qualitative or quantitative determination of a substance using living biological
material, e.g. rats, mice.

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9
Q

Cryptorchidism

A

Failure of the mammalian testes to descent into the scrotum

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10
Q

Down regulation

A

decrease in the number of receptors on a target tissue

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11
Q

Endocrinology

A

The study of the actions and interactions of the secretions of the endocrine
glands

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12
Q

Endocrine secretion

A

Secretion of a hormone from an endocrine gland which is transported in
the blood to a target organ.

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13
Q

Endocrine gland

A

A gland that secretes its product directly into the blood instead into ducts.

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14
Q

Endogenous

A

That which originates within the body.

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15
Q

Enzyme

A

A protein capable of accelerating some biochemical change in its substrate for which
it is usually specific.

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16
Q

Estrogen

A

Hormones that promote estrus and stimulate secondary sexual characteristics in
females

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17
Q

Exocrine secretion

A

Secretion of a product into a duct.

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18
Q

Exogenous

A

That which is introduced into the body from outside.

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19
Q

Feedback (positive and negative)

A

a physiological mechanism by which the secretion of a
hormone from a target organ is either inhibited (negative feedback) or stimulated (positive
feedback) when the circulating concentration of the hormone attains a specific level

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20
Q

Glycoprotein

A

Protein conjugated with a carbohydrate group.

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21
Q

Gonad

A

A primary sex gland, an ovary or testis.

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22
Q

Half life

A

the time required for one half of a substance (e.g. hormone concentration) to be
cleared from the body

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23
Q

Homeostasis

A

Maintenance of a constant internal environment. This is the goal of
physiological mechanisms

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24
Q

Hormone

A

a chemical signal that is secreted directly into the blood by an endocrine gland and
that elicits a physiological response from a target tissue

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25
Q

Hormone receptor down regulation

A

a reduction in the number of receptors for a specific
hormone

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26
Q

Hypophysectomy

A

Removal of the hypophysis (pituitary) by surgery.

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27
Q

Hypophysis

A

Pituitary gland.

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28
Q

Hypothalamic nucleus

A

a collection of nerve cell bodies in a specific location within the
hypothalamus that control a physiological response

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29
Q

Intracrine communication

A

When a hormone stimulates a cell without being secreted.

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30
Q

Kinase

A

An enzyme that phosphorylates a protein (e.g. Protein kinase).

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31
Q

Ligand

A

any substance (e.g. protein, hormone, or functional group) that binds specifically and
reversibly to another chemical entity

32
Q

Lipoprotein

A

A protein conjugated with a lipid

33
Q

Luteotropin

A

A hormone or signal that promotes the maintenance and function of a corpus
luteum

34
Q

Luteolysin

A

hormone or signal that causes the corpus luteum to regress (luteolysis)

35
Q

Morphogenesis

A

The development of form; the development undergone by an organism to
approximate to the type of its species

36
Q

Morphology

A

The science of the form and structure of organisms.

37
Q

Neurohormone

A

a hormone that is secreted directly from a neuron into the blood

38
Q

Paracrine communication

A

When a hormone stimulates an adjacent cell without entering the
blood.

39
Q

Phosphorylation

A

Addition of a phosphate group to a protein. Phosphorylation is an important
process for activating or inhibiting the biological activity of a protein.

40
Q

Physiology

A

The science which deals with the functions of the living body and its organs.

41
Q

Progestogen (Progestin)

A

A hormone that has biological activity similar to progesterone.

42
Q

Signal transduction

A

a molecular biology term in which a signal outside a cell causes a
response inside a cell.

43
Q

Steroid

A

A group name for compounds that chemically resemble cholesterol: sex hormones are
members of this group

44
Q

Steroidogenesis

A

he synthesis of a steroid by a cell

45
Q

Synergism

A

The joint action of two or more hormones or structures so that their combined
effect is greater than the sum of their individual affects

46
Q

Target organ

A

An organ that is able to respond to a hormone

47
Q

Oxytocin is synthesized in the _

A

Hypothalamus

47
Q

XXY (Kleinfelter’s syndrome)

A

Male characteristics, sterile (testes)

48
Q

XO (Turner’s syndrome)

A

Female characteristics, sterile (ovaries)

49
Q

Development stages of reproductive system

A

Indifferent, development of gonads, development of tubular reproductive tract, development of external genitalia, sexual development of the brain

50
Q

Where does the formation of genital ridges begin

A

Ventral surface of the mesonephros as paired thickenings of the coelomic epithelial layer

51
Q

What factors turn the genital ridge to the bipotential gonad

A

Wilms Tumor gene(WT1) and Steroidogenic Factor 1 (SF1)

52
Q

Primordial germ cells migrate from the _ to the _

A

Yolk sac to the genital ridge

53
Q

_ and _ form the testes

A

SRY gene and SOX 9 gene

54
Q

Role of SRY gene

A

Binds to regulatory elements on DNA to alter gene expression

55
Q

_ is the key to teste formation

A

Sertoli cell formation

56
Q

SRY

A

Sex determining region of Y chromosome

57
Q

SOX 9

A

Formation of Sertoli cells (formation of testes)

58
Q

Parts of the female tubular reproductive tract

A

Oviduct, uterus, cervix, vagina

59
Q

Parts of the male tubular reproductive tract

A

Epididymis, vas deferens, vesicular glands

60
Q

Two hormones needed for male tract formation

A

Testosterone and anti mullerian hormone

61
Q

Job of testosterone

A

Stimulate the Wolffian duct

62
Q

Job of anti mullerian hormone

A

Stops the mullerian duct from growing

63
Q

Gubernaculum

A

Elastic ligament attached to the testicles

64
Q

2 factor involved in descending the testes into the scrotum

A

Shortening of the gubernaculum (shrinkage) and increase of intrabdominal pressure to push the testes into the scrotum

65
Q

Three tissues involved with developing external genitalia

A

Genital tubercule, genital fold, and genital swelling

66
Q

Gential tubercule

A

Penis or clitoris

67
Q

Genitial fold

A

prepuce or vulva (inner)

68
Q

Genitial swelling

A

Scrotum or vulva (outer)

69
Q

_ converts testosterone to DHT

A

5 Alpha- dihydrotestosterone (forms external genitalia)

70
Q

_ converts testosterone to estrogen

A

Aromatase

71
Q

Testis->testosterone->aromatase->estrogen

A
72
Q

Estrogen binds to _

A

Alpha Fetoprotein (produced by liver)

73
Q

Ovary-> estrogen-> alpha fetoprotein

A
74
Q

Aromatization

A

Brain converts testosterone to estrogen

75
Q

Alpha fetoprotein increases during

A

late gestation