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Question 1

Principle of Dynamic Polarization

Answer 1

electrical signals within a nerve cell flow only in one direction

Question 2

Principle of Connectional Specificity

Answer 2

nerve cells do not connect indiscriminately with one another to form random networks rather each cell makes specific connections at particular contact points with certain postsynaptic target cells but not with others

Question 3

area with highest density of Na channels in

1. sensory neurons
2. inetrneurons and motor neurons

Answer 3

1. myelinated axon’s first node of Ranvier
2. axon hillock

kandel p. 30

Question 4

True or False

The binding of transmitter to receptors causes the postsynaptic cell to generate a synaptic potential. Whether the synaptic potential has an excitatory or inhibitory effect will depend on the type of receptors in the postsynaptic cell, not on the particular neurotransmitter. The same transmitter can have different effects on different types of receptors.

Answer 4

True

Question 5

Missense mutation

Answer 5

point mutation results in one amino acid in a protein being substituted for another

Question 6

Nonsense mutation

Answer 6

where a stop codon is substituted for a codon within the coding region thus resulting in a shortened protein product

Question 7

Frameshift mutation

Answer 7

small insertions or deletions changes the reading frame, leading to the production of a truncated or abnormal protein

Question 8

resting membrane potential

Answer 8

-70