Renal Flashcards
1
Q
Ciclosporin side effects
A
Hirsutism, tremor/ headaches, gingival hyperplasia, hypertension, hyperkalaemia, nausea and vomiting
2
Q
Tacrolimus side effects
A
Alopecia, tremor/headaches, glucose intolerance, neurotoxicity, hyperlipidaemia nausea, diarrhoea, hyperkalaemia
3
Q
Calcineurin inhibitors MOA
A
Inhibit calcineurin activity, preventing T cell proliferation
4
Q
Prednisolone MOA
A
Prevent production of IL-1 and IL-6 by macrophages
Inhibit all stages of T cell activation
5
Q
Prednisolone side effects
A
Moon face, osteoporosis, water and salt retention, diabetes, weight gain, behavioural disturbances
6
Q
Mycophenolate
A
Impairs T and B cell proliferation
CNI sparing agents
7
Q
Antiproliferative agent
A
Mycophenolate, azathioprine
