Reproductive Endo - Lecture 4 Flashcards

1
Q

primary male hormone

A

testosterone (T)

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2
Q

testosterone is an

A

androgen

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3
Q

which is more potent? DHEA or Testosterone?

A

Testosterone

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4
Q

5a-reductase

A

converts testosterone to DHT (most potent androgen)

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5
Q

why is it necessary for GnRH stimulation to be pulsatile?

A

necessary for gonadotropin secretion. Continuous, nonpulsatile GnRH release downregulates GnRH receptors and inhibits FSH/LH secretion

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6
Q

Estradiol (E2) feedback

A

positive feedback actions on LH secretion prior to ovulation

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7
Q

gonadal steroid feedback

A

mostly negative feedback control of GnRH and LH secretion

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8
Q

activation of steroid receptors regulates

A

gene transcription

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9
Q

gene transcription in gonads regulates:

A

gametogenesis and hormone synthesis

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10
Q

gonadal steroid regulate

A

protein synthesis in reproductive organs - breasts, uterus, male accessory glands, brain

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