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Pathology > Response to Injury > Flashcards

Response to Injury Flashcards

1
Q

what color is a scar?

A

white

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2
Q

what color is a hemorrhage?

A

red

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3
Q

Yellow color is a sign of what?

A

pus/purulent exudate

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4
Q

what is the size of a bleeding injury?

A

enlarged

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5
Q

black colored injury indicates what?

A

gangrene

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6
Q

presence of deoxygenated blood is what color?

A

blue

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7
Q

define atrophy

A

decrease SIZE of cells or organ/tissue

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8
Q

define hypertrophy

A

increase SIZE of cell or increased organ/tissue size

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9
Q

what can cause hypertrophy?

A

exercise

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10
Q

define hyperplasia

A

increase NUMBER of cells

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11
Q

what can cause hyperplasia

A

injury or endometrium

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12
Q

what is metaplasia

A

change type of cell

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13
Q

what are inclusions

A

accumulations of misfolded proteins and viruses

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14
Q

what are mallory bodies

A

cytokeratin filaments accumulated in the liver from alcoholism

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15
Q

T or F

Hyaline bodies are eosinophilic ‘hyaline’ materials found only in a cell.

A

False, can be extracellular

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16
Q

what is the function of desmin

A

ubiquitination of dysfunctional cells

17
Q

what is autophagia

A

cells eat there own content

18
Q

what is an autophagic vacuole?

A

a membrane which surrounds misfolded proteins in order to lysosomes to attach and destroy

19
Q

what are signs of cell necrosis

A

color: red
shape: tombstone
then, pyknosis, karyorrhexis, karyolysis

20
Q

what is pyknosis

A

darked nucleus; occurs during cell death

21
Q

what is karyorrhexis?

A

fragmented cells

22
Q

what is karyolysis?

A

cell disappears

23
Q

T or F

necrosis stimulates the recruitment of PMN’s

A

true

24
Q

T or F

ischemia is reduced blood flow to an organ and is irreversible

A

false, reversible

25
Q 
liquidation
ulceration
enzymatic
fibrinoid
infarction

what do these all have in common?

A

types of necrosis

26
Q

severe blood loss with irreversible damage is known as

A

infarction

27
Q

fibrinoid necrosis most commonly occurs

A

in blood vessels

28
Q

how i apoptosis different than necrosis

A

1) peripheral condensation of chromatin
2) apoptotic bodies
(caspases involved?)

29
Q

what is necroptosis?

A

a hybrid of of necrosis and apoptosis

30
Q

T or F

necroptosis is caspase independent and is initiated by TNF binding to TNFR1.

A

true

31
Q

what else other than a scar is colored white?

A

Calcified bone
loss of pigment
NECROSIS

32
Q

which one is not a characteristic of apoptosis

loss of growth factor
PMN recruitment 
activation of FAS receptor
Damaged DNA
all the above
A

PMN recruitment

33
Q

which are responsible for the activation of caspases in apoptosis

loss of growth factor
activation of FAS receptor
Damaged DNA
all the above

A

all the above

Pathology (3 decks)

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