SAS3&4

Question 1

Worked on developing a synthetic chemical effective against infection causing cells only

Answer 1

PAUL EHRLICH - 1920’S

Question 2

Who discovered penicillin

Answer 2

ALEXANDER FLEMING

Question 3

1935 the ________where introduced

Answer 3

SULFONAMIDES

Question 4

Scientist discovered penicillin in a

Answer 4

MOLD SAMPLE

Question 5

Kill the cell

Answer 5

BACTERICIDAL

Question 6

Prevent reproduction of the cell

Answer 6

BACTERIOSTATIC

Question 7

Effective against only a few microorganisms with a very specific metabolic pathway or enzyme

Answer 7

NARROW SPECTRUM OF ACTIVITY

Question 8

Useful in treating a wide variety of infections

Answer 8

BROAD SPECTRUM OF ACTIVITY

Question 9

Complex process involving chemical mediators leukocyte lymphocytes antibodies and local released and types and chemicals

Answer 9

IMMUNE RESPONSE

Question 10

Anti-effective act on a specific enzyme system or biological process;

many microorganisms that do not act on a specific system are not affected by a particular drug

Answer 10

RESISTANCE

Question 11

Microorganisms where was sensitive to the particular drug has began to develop
These results in serious clinical problems

Answer 11

ACQUIRED RESISTANCE

Question 12

Types of antibiotics

Answer 12

BACTERIOSTATIC AND BACTERICIDAL

Question 13

Substances that prevent the growth of bacteria

Answer 13

BACTERIOSTATIC

Question 14

Substances that kill bacteria directly

Answer 14

BACTERICIDAL

Question 15

Bacteria classification

Answer 15

GRAM POSITIVE
GRAM NEGATIVE
AEROBIC
ANAEROBIC

Question 16

The cell wall retains retains a stain or resist the decoloration with alcohol

Answer 16

GRAM POSITIVE

Question 17

The cell wall losses a stain or resist decolorize by alcohol

Answer 17

GRAM NEGATIVE

Question 18

Depend on oxygen for survival

Answer 18

AEROBIC

Question 19

Do not use oxygen

Answer 19

ANAEROBIC

Question 20

People traveling to areas where malaria is endemic/where in there’s certain place with endemic

Answer 20

PROPHYLAXIS OF ANTI-INFECTIVE AGENTS

Question 21

Treats gram positive bacteria and gram negative bacteria such as (Proteus Miranilis, E.coli, and klebsiella pneumonia PEcK) - WIDE SPECTRUM ANTIBIOTIC

Answer 21

FIRST GENERATION - CEPHALOSPORINS

Question 22

Treats haemophilus influenza, enterobacter aerogenes and neisseria species
Remember HENPEcK

Answer 22

SECOND GENERATION

Question 23

Are weak against gram-positive bacteria but are more potent against gram-negative as well as serratia marcescens
Remember HENPEcKS

Answer 23

3RD GENERATION

Question 24

Cephalosporins are in development

Answer 24

FOURTH GENERATION

Question 25

Large doses of cephalosporins can cause

Answer 25

NEPHROTOXICITY

Question 26

When a patient consumes alcohol while receiving cephalosporins or up to 72 hours after discontinuation of the drug, it creates a

Answer 26

DISULFIRAM-LIKE REACTION

Question 27

Action is to interfere with dna enzymes inside the bacterial cell wall which is necessary for bacterial growth and reproduction

Answer 27

FLUOROQUINOLONES

Question 28

A group of powerful antibiotic used to treat serious infections caused by gram-negative aerobic bacilli

Answer 28

AMINOGLYCOSIDE

Question 29

Action Interfere with the cell wall building ability of bacteria when they divide

Answer 29

CEPHALOSPORIN

Question 30

Similar to penicillin in structure and activity

Answer 30

CEPHALOSPORINS

Question 31

Antibiotics that interfere with protein synthesis in susceptible bacteria

Answer 31

MACROLIDES

Question 32

These are similar to macrolides about are more toxic and are effective against the same strains of bacteria

Answer 32

LINCOSAMIDES

Question 33

Action is to disrupt cell wall synthesis

Answer 33

MONOBACTAM

Question 34

Was the first antibiotic introduced for clinical use

Answer 34

PENICILLINS

Question 35

Action of these medications are interfering with cell wall synthesis

Answer 35

PENICILLIN

Question 36

These are drugs that inhibit folic acid synthesis which is necessary for the synthesis of dna and rna of the bacteria

Answer 36

SULFONAMIDES

Question 37

Develop as semisynthetic antibiotic based on the structure of a common soil mold

Answer 37

TETRACYCLINES

Question 38

They inhibit protein synthesis a leading to the inability for bacteria to multiply

Answer 38

TETRACYCLINES

Question 39

These drugs are used for the treatment of ptb or leprosy

Answer 39

ANTIMYCOBACTERIAL DRUGS

Question 40

Infection caused by a fungus is known as ___________ and it may be superficial or systemic

Answer 40

MYCOSIS