SEMINAR Flashcards
NSAIDS esp-Aspirin
increases the associated risk of gastrointestinal bleeding.
Paracetamol
enhances paracetamol metabolism into a toxic product, potentially causing liver damage.
antibiotics
disulfiram like interaction
Isoniazid and immune modulator- methotrexate
Alcohol increases the risk of liver disease.
Anticonvulsants (seizure disorders) Phenytoin
Chronic alcohol consumption induces phenytoin breakdown. reducing the desired therapeutic effect
Antihistamines gen 1,BZD,barbiturate,muscle relaxant,opioids
-additive
-enhances effects on (CNS), such as drowsiness, sedation, and decreased motor skills.
Anticoagulants ,Warfarin
-Acute alcohol intake may increase anticoagulation by decreasing warfarin metabolism;
Antidiabetic
- increase risk of hypoglycemia
- Chlorpropamide, glyburide, and tolbutamide can cause disulfiram-like interactions
cvs med-nitroglycerin
disulfiram like reaction
Tricyclic antidepressants
not only increases sedation but also risk of orthostatic hypotension