Session 1 Flashcards
Describe the course of blood flow
Heart - large elastic arteries - medium muscular arteries - arterioles - metarterioles - capillaries - post capillary venules - venules - medium veins - large veins - heart
Describe the structure of the heart
Right and left ventricles on bottom Right and left atria on top Superior vena cava on top Inferior vena cava posterior distal Pulmonary artery left Aorta on top Pulmonary veins poking out of sides
Why do we need a cvs?
Diffusion cannot occur over large distances
To supply body with needs
O2 and nutrients
Waste products carried away
Where does diffusion occur?
Capillaries
How much of exchange is done via diffusion?
98%
What is diffusion affected by?
Concentration gradient
Area
Diffusion distance
How do molecules diffuse?
Pores
Or lipid soluble molecules diffuse through capillary walls
Brains metabolic needs
Constant
0.5ml/min/g
Intolerant of flow interruption
750 ml/min to brain at all times
Heart metabolic needs
1.2 ml/min
Constant blood supply
0.9ml/min/g but if heart has to work faster it can increase four fold
Intolerant of inadequate flow
Kidney metabolic needs
High constant blood flow
Most not nutritive
Gut and liver metabolic needs
Hepatic portal system
1ml/min/g
Digestion of meal increases flow
Skeletal metabolic needs
Vary
0.3ml/min/g - 6ml/min/g
Can survive anaerobic metabolism
Skin metabolic needs
0.01ml/min/g - 1.5-2ml/min/g in thermoregulation
Why does blood flow change in some organs but remain constant in others?
Depends upon conc gradient driving exchange, flow of blood in capillaries, concentration of substances in blood entering tissue, exercise, gradient between capillaries and nearby cells