SGLT2i Flashcards
1
Q
SGLT2 MOA
A
Block SGLT2 transporter in the renal tubules
(Inhibit sodium-glucose transporter)
2
Q
SGLT2 expected change in A1c
A
Low
3
Q
How are SGLT2s administered?
A
Orally
4
Q
SGLT2 ADEs
A
Genital fungal yeast infection
UTIs/polyuria
Hyperkalemia
5
Q
SGLT2 risk of hypoglycemia
A
Low
6
Q
SGLT2 cause weight gain or loss?
A
Loss
7
Q
SGLT2 CV impact
A
Improve outcomes
8
Q
SGLT2 renal impact
A
Improve outcomes
9
Q
SGLT2 precautions/CIs
A
Elderly
Fx, pancreatitis, amputations, volume depletion
10
Q
What exam do you conduct at baseline for a px starting SGLT2
A
Foot exam
11
Q
SGLT2 cost
A
High
12
Q
SGLT2 loses efficacy when eGFR drops below?
A
45
