Skin and Soft Tissue Flashcards

1
Q

What is Impetigo?

A

Superficial skin infection
Multiple vascular lesions on an erythematous base
Golden crust = suggestive
Due to = S. aureus or Strep. pyogenes

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2
Q

What is Impetigo treatment?

A

Topical antibiotics

Large areas = topical and oral antibiotics

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3
Q

What is Erysipelas?

A
Infection of the upper dermis
Painful red area
Associated fever
Regional lymphadenopath
Distinct elevated borders
Most common = S. pyogenes
In lower limbs or face
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4
Q

What is Cellulitis?

A
Diffuse skin infection involving deep skin and fat
No distinct border
S. pyogenes and S. aureus
Fever is common
Regional lymphadenopathy
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5
Q

What are Cellulitis predisposing factors?

A

T2DM
Tinea pedis
Lymphoedema

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6
Q

What is the Treatment of erysipelas and cellulitis?

A

Anti-staph/strep antibiotics

In extensive disease = IV antibiotics

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7
Q

What is Folliculitis?

A
Pustular infection of hair follicle 
up to 5mm in diameter
Central area of purulence that may rupture
On head, back buttocks and extremities 
S. aureus
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8
Q

What is Furunculosis?

A

Referred to as boils
Single hair follicle-associated inflammatory nodule
Into dermis and sub-cut
In most, hairy and friction skin areas
S. aureus
(Obesity, T2DM, dermatitis, CKD + steroid use)

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9
Q

What is a Carbuncle?

A

Involves multiple furuncles
Neck and posterior
Purulent material
Constitutional symptoms common

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10
Q

What is the treatment of hair-associated infections?

A
Folliculitis = no treatment
Furunculosis = no treatment but may need oral antibiotics
Carbuncles = surgery and IV antibiotics
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11
Q

What is Necrotising fasciitis?

A

Emergency
Any site affected
(T2DM, surgery, trauma, PVD, skin popping)

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12
Q

What are typical organisms of necrotising fasciitis?

A
Type 1 = aerobic and anaerobic
Strep
Staph
Enterococci
Gram negative
Clostridium

Type 2 = strep pyogenes

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13
Q

What is necrotising fasciitis presentation?

A

Rapid
Erythema, extensive oedema and severe pain
Haemorrhagic bullae, necrosis and crepitus
Systemic features = hypo, tachy, delirium and organ failure

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14
Q

What is the treatment of necrotising fasciitis?

A

Surgery
Imaging may delay treatment
BS antibiotics
Overall mortality is 17-40%

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15
Q

What is Pyomyositis?

A

Purulent infection within striated muscles - manifests as an abcess
Thigh, calf, arm, glutes, chest and psoas
Fever, pain and induration of affected muscle
Untreated= septic shock
S. aureus
CT/MRI and drain with antibiotic cover

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16
Q

What is Septic bursitis?

A
Patellar and olecranon
Infection from adjacent skin infection
Swelling, fever and pain on movement
Aspirate fluid
S. aureus
17
Q

What is Infectious tenosynovitis?

A

Infection of synovial sheaths surrounding tendons
Hand commonly involved
Penetrating trauma is common cause
S. aureus and strep
Finger swelling in a semi-flexed position
Antibiotics and hand surgeon review

18
Q

What is Toxin mediated syndromes?

A

Due to superantigens
Do not activate immune system via normal contact between APC and T cell (directly to T cell)
Massive cytokine release = shock, organ failure and death
S. aureus and S. pyogenes

19
Q

What is toxic shock syndrome?

A

Fever, hypotension, macular rash, multiple organs involved
S. aureus
Production of TSST1

Strep = deep seated and higher mortality - requires debridement

20
Q

What is TSS treatment?

A
Remove offending agent
IV fluids
Inotropes
Antibiotics
IV immunoglobins
21
Q

What is Staph scalded skin syndrome?

A

Infection of S. aureus producing exfoliative toxin A or B
Widespread bullae and skin exfoliation
IV fluids and antimicrobials

22
Q

What is Panton-Valentine syndrome?

A
Gamma haemolysin
S. aureus
Cause SSTI and haemorrhagic pneumonia 
Boils which are difficult to treat
Antibiotics that reduce toxin production
23
Q

What happens in IV catheter associated infections?

A
Nosocomial infection
local inflammation progressing to cellulitis and necrosis
S. aureus
Biofilm into blood
Diagnosis by cultures
Remove and give antibiotics for 14 days
24
Q

What are the stages of surgical site infections?

A
1 = clean wound
2 = clean-contaminated
3 = contaminated
4 = infected wound