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ANP 1105 > Smooth Muscle > Flashcards

Smooth Muscle Flashcards

1
Q

What are the two layers of smooth muscle

A

Longitudial and circular

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2
Q

What layer is parallel to the long axis, and typically the outer layer

A

Longitudinal

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3
Q

What layer is perpendicular to the long axis and constricts the lumen

A

Circular

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4
Q

What is a varcosity and where would you find it

A

Swellings in the axons

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5
Q

What do varcosities store

A

Neurotransmitter

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6
Q

Unitary smooth muscle have lots of this thing so that the AP runs through all the cells

A

Gap junctions

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7
Q

Does multi unit SM contract spontaneously

A

no

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8
Q

Does unitary SM contract spontaenously

A

yes

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9
Q

where would you find unitary smooth muscle

A

Hollow organs

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10
Q

Name 3 locations you would find multi unit SM

A

Airways
Iris
Arrector pili muscles

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11
Q

What type of SM has independant fibers

A

Multi unit

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12
Q

What type of SM has fibers all attached

A

Unitary

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13
Q

What forms the lattice to transmit tension to the sarcolemma

A

Intermediate filaments

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14
Q

What anchors the intermediate and thin filaments

A

Dense bodies

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15
Q

Caveola in SM has lots of what

A

Voltage gated calcium channels

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16
Q

what is CICR

A

calcium induced calcium release

17
Q

What are the two stages of CICR

A

1) calicum enters cell through VG Ca channels in calveolae
2) calcium entry triggers SR to release more calcium

18
Q

What are the three ways for contraction in SM

A

Calcium
Hormonal/chemical
Neural

19
Q

What are the three special features of SM

A

Stress relaxation response
contraction speed
smooth muscle tone

20
Q

What allows organs to stretch really big and not be flabby once relaxed

A

The stress relaxation response

21
Q

5 steps of ca contraction

A

1) in through calveolae/SR
2) Binds to CaM
3) CaM activates MLCK
4) MLCK phosphorylates and activates myosin head
5) Cross bridge formation

22
Q

What does MLCK stand for

A

Myosin light chain kinase

23
Q

what does CaM stand for

A

calmodulin

ANP 1105 (5 decks)

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