Socul anafilactic Flashcards

1
Q

Definitie

A

reacție de hipersensibilitate sistemică severă,care produce tulburari hemodinamice grave, mediata de IgE

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2
Q

Etiologie

A

a. proteine
- veninuri de insecte, serpi, meduze
- fructe ( nuci, alune), legume (fasole)
- scoici, peste, oua
- sulfiti, tartrazina
- polen, papadie, iarba, oua
- imunoglobuline umane, toxina botulinica
- corticosteroizi, insulina, progesteron
- streptokinaza
- vaccinul antitetanic, antigripal
b. heptene
- peniciline, tetracicline, imipenem, nitrofurantion, vancomicina
- asparaginaza, ciclofosfamida
c. inhibitori de prostaglandine
- aspirina, indometacin, ibuprofen
d. factori fizici
- frigul
e. dextran
f. substanta iodata de contrast
g. vitamine
- tiamina, fitomenadion
h. anestezice locale
- lidocaina, procaina
i. protamina
j. hidrocortizon

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3
Q

Tablou clinic

A
  • greata, varsaturi, dureri abdominale, diaree
  • prurit palmo-plantar, extremitati initial calde apoi reci/cianotice, urticarie
  • tahipnee, tuse, wheezing, bronhispasm, edeme uvulare si de perete posterior al faringelui
  • tahicardie, puls filiform, hipoTA, tulburari de ritm, stop cardio-respirator
  • anxietat, confuzie, vertij, parestezii
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4
Q

Paraclinic

A
  • HLG (hemoconcentratie)
  • ASTRUP ( acidoza)
  • ionograma
  • glicemie
  • coagulograma
  • EKG
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5
Q

Diagnostic diferentiat

A
  • obstructie de corp strain
  • criza de astm bronsic
  • embolie pulmonara
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6
Q

Criterii de adminsie in TI

A
  • bronhospasm prelungit
  • hipo TA
  • hipoxie severa
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7
Q

Tratament

A
  • oprirea contactului cu alergenul
  • asigurarea libertatii cailor aeriene
  • oxigenoterapie
  • repletie volemica cu 20 ml/kg
  • Epinefrina 0,01 ng/kgc iv si/sau 0,1-0,2 ( 1:1000) la locul inocularii alergenului apoi PEV continu cu 0,05-2 microg/kgc/min
  • Metilprednisolon 2mg/kgc initial apoi 1 mg/kgc la 6 h sau HSHC 3 mg/kgc la 6 h
  • Ranitidina 0,75- 1,5 mg/kgc la 8 h
  • Salbutamol 0,01-0,06 mg/kgc aerosoli la 10-30 de min
  • Amiofilina 4-6 mg/kgc iv
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