Structure of Liver Flashcards

1
Q

what is the function of the liver?

A
  • regulation of blood sugar
  • production and regulation of lipids
  • synthesis of plasma proteins
  • transanimation to produce non-essential amino acids
  • deamination
  • detoxification
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2
Q

what is the liver?

A
  • a large active organ in the abdominal cavity
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3
Q

how does the liver receive oxygenated blood?

A
  • the hepatic artery
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4
Q

how does the blood leave the liver?

A
  • through the hepatic vein
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5
Q

what is the hepatic artery?

A
  • brings high pressure oxygenated blood into liver
  • rich in oxygen, low in waste
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6
Q

what is the hepatic portal vein?

A
  • brings low pressure blood from the intestine to the liver
  • rich in dissolved nutrients and CO2, low in oxygen
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7
Q

what the is the hepatic vein?

A
  • takes blood back into the general circulation
  • its composition is regulated with shortages made up and excesses reduced
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8
Q

what is the bile duct?

A
  • takes bile from the liver to the gall bladder (for storage)
  • OR to the small intestine where it neutralises excess stomach acids or emulsifies lipids
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9
Q

what are liver cells called?

A
  • hepatocytes
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10
Q

how are hepatocytes adapted?

A
  • lots of mitochondria
  • large nuclei
  • prominent golgi apparatus
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11
Q

what do the adaptations of hepatocytes allow?

A
  • enable a higher metabolic rate
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12
Q

what is the liver divided into?

A
  • lobules which are separated from each other by connective tissue
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13
Q

what happens to the blood delivered INTO the liver?

A
  • blood transported by hepatic artery and hepatic portal vein
  • this blood mixes with sinusoids
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14
Q

what are sinusoids?

A
  • space that is surrounded by hepatocytes (wide capillaries)
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15
Q

why is it important that blood from the hepatic artery and hepatic portal vein mixes with the sinusoids?

A
  • blood from the hepatic artery is highly oxygenated
  • blood from the hepatic portal vein is low in oxygen
  • this blood can mix and drain into the hepatic vein
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16
Q

what are kuppfer cells?

A
  • they engulf any foreign particles
17
Q

what are the sinusoids lined with?

A
  • an incomplete layer of endothelial cells
18
Q

what is the functional unit of the liver known as ?

A
  • a lobule
19
Q

why are the sinusoids lined with an incomplete layer of endothelial cells?

A
  • allows blood to reach the hepatocytes ensuring blood can be exchanged between these hepatocytes and the endothelial cells
20
Q

what is the bile canaliculus?

A
  • the flow of bile from the canaliculi to the bile duct
21
Q
A