SYMPOSIA II Flashcards
Acute diarrhoea [3]
< 4 weeks
Infectious and self limiting
Investigate after 1 week
Acute diarrhoea causes [3]
Viral - norovirus, rotavirus
Bacterial - salmonella, s aureus
Parasitic
Chronic diarrhoea [2]
> 4 weeks
Chronic pathology
Always investigate
Chronic diarrhoea causes [4]
Colonic
Small bowel
Pancreatic
Endocrine
Parasitic examples [3]
cryptosporidium parvum, giardia lambila, entamoeba histolytica
IBS
continuous mucosal inflammation of the colon without granulomas on biopsy, affecting the rectum and a variable extent of the colon and characterised by a relapsing and remitting course
UC
bloody diarrhoea, rectal bleeding, mucus, faecal urgency, abdominal pain, nocturnal defecation
Any age and gender
Relapsing / remitting course
Ex-smokers 70% increased risk of UC
Smoking/Appendectomy protective
UC treatment
Normal - hydrocortisone, heparin, stool chart, AXR, daily CRP
Mild- moderate - mesalazine, prednisolone, azathioprine
Severe - infliximab (TNF inhibitor), cyclosporin, colectomy
Avoid NSAID’s, opiated, anti-motility agents
UC treatment - normal
hydrocortisone, heparin, stool chart, AXR, daily CRP
UC treatment - moderate
mesalazine, prednisolone, azathioprine
UC treatment - severe
infliximab (TNF inhibitor), cyclosporin, colectomy
CD
discontinuous and often granulomatous and transmural inflammation affecting any area of the gastrointestinal tract
Chronic diarrhoea, IBS symptoms, abdominal pain, weight loss, anaemia, growth failure, blood and mucus in stool, perianal disease, extraintestinal manifestations
CD treatment
prednisolone, azathioprine, methotrexate, nutrition, antibiotics, infliximab, surgery