Systemic manifestation of disease Flashcards

1
Q
A
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2
Q

Gross function of different skin cells

A

Keratinocytes: Barrier
Melanocytes: Pigment
Langerhans cells: Immune
Merkel Cells: Sensory

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3
Q

When should you consider systemic disease with skin symptoms?

A

Constitutional symptoms. Signs and symptoms that relate to other body symptoms

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4
Q

What is Jaundice caused by?

A

Build up of urobilinogen that is deposited into skin and mucous membranes

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5
Q

Cholestatic Jaundice

A

Unrelenting itching. Caused by slowing or topping of bile flow (often due to a blockage from liver to gallbladder or GB to small intetestine)

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6
Q

Spider angiomata

A

Vascular lesions with central arteriole surrounded by many smaller vessels. Commonly on trunk, face, and upper limbs

Thought to be from alterations in sex hormone metabolism related to cirrhosis

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