Term Test Flashcards
Prokaryotes have _____ ribosomes
70s
eukaryotes have _____ ribosomes
80s
mitochondria have ______ ribosomes
70s
what is the initiating amino acids for eukaryotes?
methionine
what is the initiating amino acid for prokaryotes and mitochondria?
N- Formylmethionine
aerobic respiration uses ______ while fermentation ______
oxygen, doesn’t
differentiate the extrinsic and intrinsic pathway in apoptosis
intrinsic: cytochrome C, capsases then cell death
extrinsic: death receptors, capsases, cell death
what are the 3 different ways mitochondria can lead to loss of function?
- generation of ROS the byproduct of mitochondrial oxidative phosphorylation leading to deleterious mutations
- introduction of excess mutations in mtDNA causing increases in ROS
- when proteins are released that lead to the process of apoptosis, cell death or aging
what are th key roles for mitochondria?
- ATP synthesis coupled to electron transport
- Translation of mitochodnria proteins
- Iron sulfur cluster biogenesis
- cell death
describe how a mitochondrial gene can be transfered to the nulceus
. The mitochondrial mRNA must be reverse-transcribed and the resulting DNA integrated into a nuclear chromosome. DNA elements for expression of the gene and for directing the protein to the mitochondrion must then be assembled with it. If this takes place, the mitochondrial gene copy can be deleted without loss of function.
what are key elements for transferring a mitochondrial gene to the nucleus?
- addition of promoter
- Terminator
- targeting sequence
nucleus first mitochondria later model
bacteria and archaea, two separate events that created the nucleus first then the mitochondria was created much later
mitochondria nucleus co origin model
both the mitochondria and nucleus were created in the same event
alternative hypothesis describing the origin or eukaryotic cell
simultaneous creation of the eukaryotic nucleus and mitochondria by fusion of a hydrogen requiring methanogenic archaebacterium with a hydrogen producing alpha proteobacterium symbiont
Slide 8 ** Lecture 15
Slide 8 *** lecture 15
Steps of nucleus first model and co origin model
what are the two different theories for how mitochondria came in the nucleus first model?` slide 12 lecture 15**
- alpha proteobacteria enters host cell , gene tansfer and gene losss, this proteobacteria stays
- there is a loss of the alpha proteobacteria and a anaerobic eubacterium enters host cell, gene transfer and gene loss occurs
what are the two different theories for how mitochondria came in the nucleus first model?` slide 12 lecture 15**
- alpha proteobacteria enters host cell , gene tansfer and gene losss, this proteobacteria stays
- there is a loss of the alpha proteobacteria and a anaerobic eubacterium enters host cell, gene transfer and gene loss occurs
________ clusters exist in mitochondrial DNA
coding
cyanobacteria uses ________
photosyntheis