test 3 Flashcards
Pigmented area around nipple
Areola
What do sertoli cells synthesize?
ABP (androgen binding protein)
How does corpus spongiosum begin? What is it covered by?
As bulb of penis covered by bulbospongiosus muscle.
Increased basal body temp, changes in cervical mucus, cervix softens, Mittelschmerz pain
Signs of ovulation
Phases of Meiosis II?
prophase II, metaphase II, anaphase II, telophase II, cytokinesis
Where are sertoli cells?
seminiferous tubules
Packets of discarded DNA, the secondary oocyte receives most to the cytoplasm and organelles
Polar bodies
What are the steps of meiosis I?
Prophase i, metaphase i, anaphase i, telophase i, cytokinesis
Sertoli cell AKA
sustentacular cell
Where do ALL STAGES OF SPERM DEVELOPMENT occur?
Seminiferous tubules
Spermatids are (X & Y together/X or Y).
X or Y (normal)
Why is Meiosis I called reduction division?
I️t reduces number of chromosomes to half (1n - haploid)
Milk-secreting glands open by ____________ ducts at the nipples.
Lactiferous
What cells extend from basement membrane to lumen?
Sertoli cells
In the testes there are septa that form what?
200-300 compartments called lobules
Starting at puberty, each month, hormones cause _____ to resume in several follicles so that ______ is reached by ovulation. However, usually only one ______ reaches maturity and is ovulated.
Meiosis 1; metaphase of meiosis 2; oocyte
Increasing _______ levels trigger the secretion of _______ in the ovary in the preovulatory phase (follicular phase)
Estrogen; LH
Spermatids are (unique/the same).
unique
What is required to initiate and maintain male sexual behavior?
Testosterone
What are the four stages of mitosis, meiosis I️ & II?
Prophase, metaphase, anaphase, telophase (PMAT)
Ovary in postovulatory phase (luteal phase): if fertilization did not occur- as ovarian hormone levels drop near the end of the cycle, secretions of ______, ______, and _____ rise.
GnRH, FSH, and LH
Genetic Recombination produces ____________________________
sister gametes that are unlike each other and unlike either parent. (Prophase I, Meiosis I)
What is “independently assorted”?
Maternal and paternal homologous chromosomes
what is the difference between secondary spermatocyte and spermatid?
secondary has replicated chromosomes
What does midpiece of sperm contain?
mitochondria to form ATP
Diploid cells consist of ______ pairs of chromosomes for a total of ________
23, 46
Semen contains ____________ plus __________________.
sperm, glandular secretions
Somatic cells AKA ___________ cells.
diploid
The seminal vesicles _____________________ in the vagina & in the male urethra.
neutralize acidity
When would a semen analysis be bad news?
if it reveals lack of forward motility, low count, or abnormal shapes
The mucosal layer of the vagina contains what type of epithelium and connective tissue? What does it have large storage of?
Stratified squamous epithelium and areolar connective tissue. Has large stores of glycogen breakdown to produce acidic pH
_________ have an X and a smaller Y chromosome.
Males
Normally flagella are _____________, have ____________ movement, and function is to _____________________.
alone, whip-like, propel cell within media
Loose CT that binds it to other organs (vagina)
Adventitia layer of the vagina
What is secreted by the hypothalamus and controls the female reproductive system
GnRH
Reasons for hysterectomy
- Endometriosis 2. Ovarian cysts 3. Excessive bleeding 4. Cancer cervix, uterus, or ovaries
What is the paired oval glands of male reproductive system (2x1 in)?
Testes
At puberty, one with a 5 alpha-reductase deficiency will present with?
breasts failing to develop, masculine characteristics appear, internal exam see testes
What is an acrosome?
a membranous sac containing hyalurodinase and proteinase enzymes (help with ECM breakdown and movement to egg)
What is purpose of alkaline mucus that cowper’s gland secretes?
It neutralizes acids and lubricates
Dihydrotestosterone (DHT) is (more/less) potent than regular testosterone.
more
Inhibits the secretion of FSH
Inhibin
How does corpora cavernosa begin?
as crura of penis attached to ischial and pubic rami
Are hernias more common in males or females?
Males
Semen is a mixture of what 2 things?
Sperm and seminal fluid
what is corpora cavernosa covered by?
ischiocavernosus muscle
Capsule of dense connective tissue around ovaries-under germinal epithelium
Tunica albuginea
What stimulates Leydig cells to secrete testosterone?
LH
The tail region of the epididymis continues as _______________.
ductus deferens
Daughter cells of mitosis have (the same/different) number of chromosomes from the parent.
Same
5 functions of sertoli cells:
- support developing sperm cells 2. produce fluid & control release of sperm into the lumen 3. secrete inhibin which slows sperm production by inhibiting FSH 4. synthesize ABP 5. form blood-testes barrier
Why does a baby with deficiency of 5 alpha-reductase externally look like a female?
due to lack of DHT during development
What is product of Meiosis 2 of spermatogenesis?
Spermatids
What is testicular feminization?
recessive (x-linked) disorder where receptor for testosterone is defective
What is result of Meiosis I?
2 cells with haploid number of chromosomes generally distinct
What stimulates spermatogenesis?
FSH
During an erection, blood enters the penis doing what?
compression veins, so blood is trapped
After puberty, _______ complete meiosis 1, which produces ________ and a first polar body that may or may not divide again
Primary oocytes; secondary oocyte
The spiral arterioles supply what….
Stratum functionalis of endometrium
How many chromosomes are in secondary spermatocyte?
23 (haploid)
Surgical removal of the uterus
Hysterectomy
Composed of 3 layers of smooth muscle in the uterus
Myometrium
What hormone is high in the fetus, and drops once nursing for long periods?
Prolactin levels
In crossing over of prophase I of meoisis, parts of ______________ chromosomes may be exchanged with ________________ ones.
maternal, paternal
What four things does prostate gland do/supply?
- citric acid 2. enzymes for liquefication 3. PSA (prostate-specific antigen) 4. seminalplasmin (antibiotic)
______ levels rise as follicle matures, so you are ready to ovulate. Pituitary is told to release ________ to start ovulation
Estrogen; LH
Sertoli cells support ___________________.
developing sperm cells
What is a form of male sterilization where vas deferens is cut off and tied?
Vasectomy
6-7 layer granulosa cells surround oocyte
Primary follicle
Narrow, 4 inch tube, that extends from ovary to uterus and is open at both ends
Uterine/ Fallopian tubes
What are all structures passing to and from the testes?
- testicular artery 2. Pampiniform Plexus of Veins 3. autonomic nerves 4. lymphatic bessels 5. vas deferens 6. cremaster “CLAP TV”
Which process is referred to as reduction division?
Meiosis I️
What is a 2 inch long tunnel passing through the 3 muscles of the anterior abdominal wall - weakens wall?
Inguinal canal
What forms the blood-testes barrier?
sertoli cells
Antrum forms in what stage of follicular development
Secondary follicle
How do somatic cells divide?
Mitosis
What allows for normal gene products from any haploid cell to complement defective cells?
Cytoplasmic bridge.
What hormones stimulates theca cells?
LH
When does independent assortment occur?
During Meiosis I
What is glans penis covered by?
loosely fitting prepuce or foreskin
what is the post-ovulatory phase called in the uterus?
secretory phase
What stimulates smooth muscle contraction in theca helping with ovulation
LH
2 functions of Vas Deferens?
- Convey sperm along through peristaltic contractions (need long and circular mm) 2. Store sperm viable for several months
Where does sperm reach the oocyte
In the ampulla
Preparation of uterus to receive fertilized ovum, and if implantation does not occur, the stratum functionalis is shed during menstruation
Uterine cycle
Most common cause of breast lumps, cysts and thickening of alveoli develop
Fibrocystic disease of the breasts
During sexual arousal, what does bulbourethral gland secrete?
Alkaline mucus into spongy urethra
Region just deep to tunica in the ovary, contains the follicles
Cortex
Outer serous membrane of Fallopian tube
Serosa layer of Fallopian tube
What regions does epididymis have?
Head, body and tail
Is testosterone production negative or positive feedback?
negative
Transport the fertilized ova
Uterine tubes
What branches penetrate to the endometrium
Straight and spiral branches
________ begins in meiosis 2 but stops in metaphase
Secondary oocyte
What does seminal vesicles secrete?
Alkaline, viscous fluid
How many layers of the vagina are there? What are they?
3: mucosal, muscularis, adventitia
What is ovulated?
A secondary oocyte and the first polar body
_______ Hysterectomy removes uterus, tubes, ovaries, part of vagina, pelvic lymph nodes, and supporting ligaments
Radical
What is the sac of loose skin, fascia, and smooth muscle divided into two pouches by a septum?
scrotum
Millions present a birth, then atresia occurs, but only 400 mature during a woman’s life
Primary oocytes
When are estrogen levels highest in the uterine cycle? Why are they highest during this time?
Preovulatory phase because follicles are growing producing more and more and its an anabolic hormone promoting rebuilding
How many layer to the Fallopian tube? What are they?
3: mucosa, muscularis, and serosa
Most immature follicle cell?
Primordial
Oocytes and surrounding follicular cells make up what?
Follicles
Testosterone & DHT bind to ___________________ and change ______________.
intracellular receptors (Lipid-soluble), genetic activity
What is the likeliness of cryptorchidism in a full-term baby vs. a premature infant?
3%, 30%
When does crossing over occur?
Meiotic Prophase I
___________ have two X chromosomes.
Females
Mature follicle, oocyte within is arrested at metaphase of meiosis II at ovulation time
Graafian follicle
What type of reproduction creates genetic diversity? By what process?
Sexual through Meiosis 1 and 2
What happens to the daughter cells produced by spermatogonium? Haploid/Diploid?
One daughter cell kept in reserve One differentiates into primary spermatocyte BOTH DIPLOID
(Sympathetic/parasympathetic) reflex causes ejaculation.
sympathetic
Why is sperm adapted?
to reach and penetrate a secondary oocyte
Inhibin causes the stimulation or inhibition of what hormones?
Inhibits secretion of FSH and LH
Gametes consist of how many chromosomes?
SINGLE SET of 23 chromosomes
During fetal development, germ cells from yolk sac migrate to ovary and become ______?
Oogonia
A spermatogonium is (X & Y together/X or Y).
X & Y together
What muscle is found in spermatic cord?
Cremaster
The descent of testes develops near what?
kidney on posterior abdominal wall
What is the study of the urinary system and the male reproductive system?
Urology
What is the pathway of ductus (vas) deferens?
- Ascends along posterior border of epididymis 2. Up through spermatic cord and inguinal lig 3. Reaches posterior surface of urinary bladder 4. empties into prostatic urethra with seminal vesicle
During fetal development, ______ begins but stops in prophase.
Meiosis 1
Primary spermatocytes are (haploid/diploid).
diploid
Before puberty, what does testosterone do?
Small amounts of test inhibit GnRH release
Where do you need blood tests barrier in spermatogenesis?
between 1 & 2 spermatocyte
How does prostate change with age?
it enlarges
Facilitates implantation in the relaxed uterus
Relaxin
What is single organ the size of a chestnut found inferior to the bladder with many duct openings?
Prostate gland
What does prostate gland secrete?
milky, pH 6.5 fluid
What stimulates final steps in spermatogenesis?
Testosterone
What is purpose of muscularis layer of fallopian tube, and what is it composed of?
Use peristalsis to help move the ovum down the uterus / Circular and longitudinal smooth muscle
Glycoprotein layer between oocyte and granulosa
Zona pellucida
The seminal vesicles produce prostaglandins to?
stimulate sperm motility and viability (regulation of smooth muscle)
Where are Leydig cells located?
between seminiferous tubules
Spermatogonium reproduce by (mitosis/meiosis I/meiosis II).
mitosis
What are the two major contributions to reassortment of genetic material?
Independent assortment and crossing over
What hormone acts on granulosa cells?
FSH
What is synapsis in prophase I of meiosis?
all copies of homologous chromosomes pair off forming a tetrad
Testosterone _____________ sexual behavior and libido, increases _______________ and ___________ the voice in puberty.
increases, male metabolism (bone/muscle mass increase), deepens
Passageway for birth, menstrual flow, and intercourse
Vagina
High levels of estrogen (without progesterone) cause the stimulation or inhibition of what hormones?
Stimulation of GnRH, LH, and FSH (Androgens)
What 3 places are testosterone produced?
- Interstitial (Leydig) 2. Adrenal Cortex 3. Sustentacular (Sertoli) Cells
What does Meiosis II have in common with mitosis?
CENTROMERES SPLIT SISTER CHROMATIDS SEPARATE and move towards opposite poles of the cell
Each chromosome of secondary spermatocyte has?
2 chromatids joined by centromere
Gametes are (haploid/diploid).
haploid
Shed during menstruation
Stratum functionalis
What is loop of intestine protruding through the deep ring?
Indirect hernia
Meiosis II from secondary spermatocytes to spermatids separates ______________.
split sister chromatids