thrombocytopenia

Question 1

what are problems with production of platelets?

Answer 1

Sepsis

B12 or folic acid deficiency

Liver failure causing reduced thrombopoietin
production in the liver

Leukaemia

Myelodysplastic syndrome

Question 2

which things can cause destruction of platelets?

Answer 2

Medications (sodium valproate, methotrexate, isotretinoin, antihistamines, proton pump inhibitors)

Alcohol

Immune thrombocytopenic purpura

Thrombotic thrombocytopenic purpura

Heparin-induced thrombocytopenia

Haemolytic-uraemic syndrome