Tinea Versicolor Flashcards
Other names of tinea versicolor
Pityriasis versicolor
Liver spots
Chromphytosis
Dermatomycosis furfuracea
Tinea flavea
Causative organism of TV
Malasesia globosa
Furfur
Sympodialis
Restricta
Obtusa
Sloofiae
Dermatitis
Pschydermatis
Nana
Japonica
Yamatoensis
Caprae
Cuniculae
Equin
Common morphology of malasezia organism in normal skin and lesional skin
Normal skin- yeast form
Lesional skin- mycelial form
TV lesions of palms and soles caused by
Pachydermatis- as it is not lipophilic
Morphological variants of TV
Chromic
Achromic
Pseudochromic
Macule
Patch
Papule
Plaque
Follicular
Perifollicular
Atrophic
Erythematous
Icthyosiform
Anular
PR like
Reason for hypopigmentation in TV
Dicarboxylic acid produced by fungi - inhibits tyrosinase
Direct cytotoxic effect on the melanosomes
Smaller size of melanosomes
Decreased total epidermal pigmentation
Increased space b/w melanocytes and keratinocytes
Reason for hyperpigmentation in TV
Increased melanosomes size
Thicker keratin layer
More fungal load- stimulating melanocytes
Increase in number of melanosome
Wood’s lamp finding in TV
Light yellow colour fluorescence due to pityra lactone
KOH in TV
10 % KOH used
Finding- small broken filaments with thick walled yeast cells
Giving spaghetti and meatball or banana and grape appearance
Histopathology in TV
Hyperkeratosis, parakeratosis
Slight acanthosis
Increased pigmentation in basal layer
Fungal elements- seen as filaments both in between and inside keratinocytes
Culture media used for TV
Culture characteristic in TV
Media used;
SDA with olive oil
Dixon medium with olive oil
Actidione
Tween 20
SDA with chloramphenicol
Culture findings:
Yeast like buff colonies
Reverse dome shaped colonies when incubated with 70% co2 in atmospheric air
Special stains used
India ink
PSA
Calcoflour white
May gunwale giemsa stain
Methylene blue
Parker 5%
Lactophenol blue
Chicago stain with KOH 8%
Treatment options for TV
Topical Azoles twice daily for 2-3 weeks- clotrimazole, miconazole, econazole, ciclopiroxolamine, ketaconazole , terbinafine 1% be 2-3weeks
2.5% selenium sulphide applied below neck over night application alternate nights for 2 weeks. OR 5-10 mins for 7-10 days
20% sodium hyposulphite
50:50 propylene glycol in water
Ketaconazole shampoo twice weekly for 2-3 weeks
Oral treatment for TV
Itraconazole 200 mg for 5 days
Fluconazole 150-300mg od 14 days
Fluconazole 400mg stat
Itraconazole 600 mg stat dose
Common age for TV
Rare in children- due to less sebaceous glands
Common in late teens
