Topic 1: 4 Flashcards
permeability
measure of the ease with which a substrate can penetrate a membrane
osmosis driven by
osmolarity of solutions
osmotic pressure
tendency for water to move down its gradient
osmolarity
depends on number of ALL solute particles in solution (including dissociated substances)
Osmolarity= concentration (mM/M) x no. of particles (expressed in mOsm/Osm)
hypo osmsotic
solution with lower number of particles per litre of solution than another
exerts a higher pressure than the other solution for water to move
hyper osmotic
solution with a higher number of particles per litre of solution than another
exerts a lower pressure than the other solution for water to move
iso osmotic
two solutions have the same number of particles per litre of solution
exert the same pressure on water to move
RBC osmotic pressure
280 mOsm
Tonicity
explains fate of a cell
NPP only
Saline
150mM NaCl is iso osmotic and isotonic to the RBC so it is known as 100% physiological saline