TOPICAL CYTOTOXIC AND IMMUNOSUPPRESIVE AGENTS

Question 1

Give the Cytotoxic drug classes

Answer 1

Antimetabolites - methotrexate , Fluorouracil
Alkylating agents
Microtubule Inhibitors - Vinblastine and Podophyllin
Other cytotoxic agents - Bleomycin , Ingenol mebutate , Alitretinoin , Bexarotene

Question 2

Give the Immunosuppresive agents

Answer 2

Calcinuirin inhibitors
mTOR inhibitors

Question 3

Give the MOA for Fluorouracil

Answer 3

Blocks DNA methylation in DNA synthesis