Toxic Principles- Plant Alkaloids Flashcards

1
Q

Colichicine

A

Autumn crocus, meadow saffron- Lily family, Glory lily, climbing lily.

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2
Q

Colichicine (MOA)

A

Loves rapidly dividing cells. Affects all systems- GI, Resp, Cardio, Renal, Hepatic, Neuronal, coagulation, myelosuppression.

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3
Q

Diterpene alkaloids

A

Buttercup* (has a lot of other toxins, too). Delphinium, monkshood, etc. Larkspur.

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4
Q

Diterpene alkaloids (MOA)

A

Competitively blocks nicotinic receptors at NMJ (curare-like). Cows = sudden death.

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5
Q

Ergot

A

Fungi on moldy corn

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6
Q

Ergot (MOA)

A

Vasoconstriction and gangrene therefore hair/hoof sloughing.

uterine contraction therefore abortion

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