Tube and cancer facts

Question 1

Type 1 tumours

Answer 1

• Low grade
• Slow growing
• Endometrioid, clear cell, mucinous, low-grade serous carcinoma, Brenner
• Multifocal distribution, distant recurrence, systemic spread

Question 2

Type 2 tumours

Answer 2

• Serous tubal intraepithelial carcinoma (STIC)
• High-grade serous carcinoma, carcinosarcoma, undifferentiated
• Advanced stage, abrupt
• Mesothelial lined surfaces of the ovary, fallopian tube and peritoneum
• 10% of women with ovarian cancer have a positive family history and a heterozygous mutation in BRCA1 or BRCA2

Question 3

BRCA 1

Answer 3

• Lifetime risk of developing ovarian cancer is as high as 25–50%
• Develop in their 40s
• Risk reducing BSO reduces risk by 80 %

Question 4

BRCA 2

Answer 4

• 10 - 20 % lifetime risk

- Risk reducing surgery reduces risk by 77 %