Unit 2: Biomechanics of Skeletal Tissue Flashcards

1
Q

What .are the principal types of skeletal tissue?

A

Epithelial tissue
Connective tissue
Muscle tissue
Nervous tissue

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2
Q

What are the 4 types of bone shape?

A

Long bones
Short bones
Flat bones
Irregular bones

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3
Q

What cells is bone made of?

A

Osteocytes

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4
Q

What is the non-cellular component of bone?

A

Strong collagen fibres embedded in ground substance (jelly-like matrix) - flexible but resist stretching

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5
Q

What minerals make of the inorganic component of bone?

A

Calcium & phosphate (in the form of calcium phosphate crystals) - responsible for hardness & rigidity

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6
Q

What are the 2 types of bone tissue?

A

Cortical (compact) bone

Cancellous (spongy) bone

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7
Q

What is cortical bone?

A

The outer dense layer of bone

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8
Q

Where is cancellous bone found?

A

Inner part of short, flat & irregular bones - also lines inner surfaces and makes up greater part of metaphyses and epiphyses

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9
Q

What is the structure of cancellous bone?

A

Mesh-like structure (spaces in the mesh contain red bone marrow)

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10
Q

What is the basic structural unit in cortical bone?

A

Haversian system

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11
Q

What are the layers in cortical bone tissue called?

A

Lamellae

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12
Q

What is contained within the haversian canals in cortical bone?

A

Blood vessels & nerve fibres

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13
Q

What are the cavities between lamellae called?

A

Lacunae

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14
Q

What is contained within lacunae?

A

Osteocytes

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15
Q

What links haversian canals and lacunae?

A

Canaliculi

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16
Q

What surrounds each haversian system?

A

Cement-like ground substance

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17
Q

What is the weakest point of bone’s microstructure and why?

A

Ground substance because it contains no collagen fibres

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18
Q

What are the basic structural units in cancellous bone?

A

Trabeculae

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19
Q

What is the main difference between the structural units of cortical and cancellous bone?

A

Trabeculae (cancellous) do not contain haversian canals

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20
Q

Why do trabeculae not contain haversian canals?

A

Not needed in cancellous bone as blood vessels pass through the marrow filled spaces between the lattice work of trabeculae

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21
Q

What is the difference between tension & compression?

A
Tension = acting to stretch material 
Compression = acting to compress material
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22
Q

Define stress

A

Force per cross-sectional area

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23
Q

Define strain

A

The change in length divided by the original length (measure of the deformation a material has undergone)

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24
Q

What are the units of strain?

A

Strain has no units (it is a ratio)

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25
Q

In what region is stress directly proportional to strain?

A

Elastic region

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26
Q

What is the point at which a bone fractures called on the stress-strain graph?

A

Ultimate strength/strain

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27
Q

What does Young’s Modulus describe?

A

How flexible or stiff a material is

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28
Q

If Young’s Modulus is small does this mean the material is stiff or flexible?

A

Flexible

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29
Q

How is Young’s Modulus (E) calculated?

A

E = stress/strain

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30
Q

What are the 5 types of loading?

A
Tension 
Compression 
Bending 
Shear 
Torsion
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31
Q

What is shear loading?

A

When 2 forces at in opposite direction to cause layers within a material to slip or shear

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32
Q

Give 2 examples of shearing in orthopaedics?

A
  1. Screw in fracture fixation plate

2. Bone cement being sheared by hip prosthesis & bone

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33
Q

Is human cortical bone weaker or stronger in shear than in tension & compression?

A

Shear (although shear fractures are rare)

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34
Q

Name the 2 common types of bending

A

Cantilever bending

Three point bending

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35
Q

Give an example of a bending fracture

A

‘Boot top’ fracture in skiers

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36
Q

When do torsional loads occur?

A

When a bone is twisted about its longitudinal axis

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37
Q

What characteristic appearance to fracture have that are caused by torsional loads?

A

Spiral

38
Q

In torsional loads on a bar where are stress & strain the greatest?

A

Outer surface

39
Q

Which type of load are long bones designed to be resistant to?

A

Torsional loads (thick outside hollow inside)

40
Q

Where is the most common site of a fracture caused by a torsional load?

A

Tibia (distal as smaller cross-sec area)

41
Q

How do muscles alter the stress distribution in a bone?

A

Produce overall compressive loading (as bones stronger in compression)

42
Q

Why are tired athletes more likely to fracture a bone?

A

Muscles are fatigued and therefore unable to control the distribution of stress within their bones

43
Q

What is Wolff’s law?

A

Bone is laid down where needed and resorbed where not needed

44
Q

What is bone atrophy?

A

When inactivity leads to the resorption of bone tissue

45
Q

When can bone remodelling cause a problem in fracture healing?

A

If plate not removed after fracture has healed bone will weaken (stress shielding)
Points at which screws are inserted there will be bone hypertrophy as these sites carry extra load

46
Q

What is a fatigue fracture?

A

Fracture resulting from repeated application of a load that is smaller than the ultimate strength of the bone

47
Q

In which age group are greenstick fractures more common in and why?

A

Children - bones are less brittle than adults are they contain greater proportion of collagen

48
Q

What is a greenstick fracture?

A

Incomplete fracture whereby one side of the bone is bent and the other side is buckled (caused by bending or torsional loads)

49
Q

What causes the large reduction in the amount of cancellous bone tissue with age?

A

Thinning of longitudinal trabeculae

Resorprtion of some transverse trabeculae

50
Q

What are the 3 types of cartilage?

A

Hyaline cartilage
Elastic cartilage
Fibrocartilage

51
Q

Where is hyaline cartilage found?

A

Covers the articular surfaces of bones in synovial joints also forms tip of nose

52
Q

Where is elastic cartillage found?

A

Eternal ear & epiglottis

53
Q

Where is fibrocartilage found?

A

Symphysis pubis & intervertebral discs

54
Q

What is articular cartilage?

A

Form of hyaline cartilage found on the articulating ends of bones in synovial joints

55
Q

What is the purpose of articular cartilage?

A

Cushions bones while providing a mooth lubricated bearing surface that limits contact stress and wear

56
Q

Describe the structure of articular cartillage

A

Organic matrix (mainly collagen) fibrils) interspersed with chondrocytes and a conc solution of proteoglycans

57
Q

Where are chondrocytes most concentrated in articular cartilage?

A

Deeper layers adjacent to the bone

58
Q

Where are proteoglycans most concentrated in articular cartilage?

A

Middle portion

59
Q

What are the 3 structural zones of articular cartilage?

A

Superficial tangential zone
Middle zone
Deep zone

60
Q

What is the structure of the superficial tangential zone?

A

Collagen fibrils tightly woven into sheets arranged parallel to the articular surface and chondrocytes are are oblong with their longitudinal axis aligned parallel to the articular surface

61
Q

What is the structure of the middle zone of articular cartilage?

A

Collagen fibrils are arranged more randomly but still broadly parallel to articular surface. They are less densely packed to accomodate the high conc. of proteoglycans and the chondrocytes are circular and randomly distributed

62
Q

What is the structure of the deep zone of articular cartillage?

A

Collagen fibrils arranged in larger fibre bundles that are anchored in underlying bone tissue. Chondrocytes are arranged in loose columns aligned perpendicular to the ine dividing the articular cartilage and underlying bone

63
Q

What lies below the deep layer in articular cartilage?

A

Thin layer of calcified cartilage (gradually merges into bone)

64
Q

What is the interface between the articular cartilage and calcified cartilage beneath called?

A

Tidemark

65
Q

What mechanical behaviour does articular cartilage exhibit?

A

Viscoelastic

66
Q

What is creep?

A

When viscoelastic material is subjected to constant load. Initial rapid deformation is followed by a slowly increasinf deformation.

67
Q

Describe how creep occurs within articular cartilage

A

Fluid is rapidly forced out of the cartilage then it reaches equilibrium. Fluid flow ceases completely and the applied load is borne entirely by the solid matrix. At equilibrium majority of the fluid still remains in the articular cartilage

68
Q

What is stress relaxation?

A

When a viscoelastic material is kept at constant deformation the stress is reduced over time

69
Q

What is the difference between the coefficients of friction between synovial joints and artificial joints?

A

Synovial joint = low (0.02)

Artificial joints = higher (0.03-0.1)

70
Q

What 2 factors is how lubrication is brought about dependent on?

A

Magnitude of the load

Length of time the load is maintained

71
Q

What are the 3 main types of lubrication?

A

Elastohydrodynamic lubrication
Boosted lubrication
Boundary lubrication

72
Q

What is elastohydrodynamic lubrication?

A

When 2 surfaces, one of which is deformable, are ubricated by a film of fluid as they move relativ eto one another.

73
Q

Do the 2 surfaces touch in elastrohydrodynamic lubrication?

A

No (separated by fluid#)

74
Q

What is it called when 2 surfaces slide over each other?

A

Hydrodynamic lubrication

75
Q

What is it called when 2 surfaces move closer together

A

Squeeze film lubrication

76
Q

Describe hydrodynamic lubrication?

A

When 2 surfaces slide over one another they form a wedge of fluid. As surfaces slide a lifting pressure is generated

77
Q

Describe squeeze film lubrication

A

Cushions and protects surfaces but if high loads are maintained lubricant will eventually be depleted

78
Q

Why does a deformable surface reduce pressure on a joint in elastohydrodynamic lubrication?

A

Deformation of the surface increases the area over which the load is disributed

79
Q

What problem does boosted lubrication solve?

A

That if to lubricated surfaces are forced together over a period of time eventually the lubricant will be completely depleted (squeezed out)

80
Q

Describe boosted lubrication

A

As gap between 2 articulating surfaces decreases the resistance to the sideways flow of the lubricant becomes greater than the resistance of flow of the small molecules into articular cartilage. Water molecules move and leave a thick viscose gel (enriched lubricant)

81
Q

What problem does boundary lubrication solve?

A

Fluid of film present between two surfaces is not thick enough to prevent contact

82
Q

Describe boundary lubrication

A

Lubricant molecules attach themselves chemical to surfaces creating a boundary layer

83
Q

How does a boundary layer help prevent wear in joints?

A

Has a low shear strength and therefore lower friction than the bare surfaces

84
Q

What is the name of the protein from the synovial fluid that coats articular cartilage?

A

Lubricin

85
Q

What is a tendon?

A

Soft connective tissue that connects muscle to bone

86
Q

What is a ligament?

A

Soft connective tissue that connects bone to bone

87
Q

What cells are found in tendons & ligaments?

A

Fibroblasts

88
Q

How are collagen fibres arranged in tendons & why?

A

Arranged completely in parallel as they need to withstand loads in one direction only

89
Q

How are collagen fibres arranged in ligaments & why?

A

Not arranged completely in parallel as although need to with large large loads mainly in one direction they also need to withstand small loads in other directions

90
Q

What mechanical behaviour do tendons & ligaments exhibit?

A

Viscoelastic behaviour

91
Q

What is the anatomical position of the ACL?

A

Centre of the knee joint with one end joined to the femur and the other to the tibia

92
Q

How far can the ACL be elongated before it fails completely?

A

Around 7mm